中医特色护理方案改善湿热瘀结型盆腔炎的效果研究

Effectiveness of a Traditional Chinese Medicine-Based Nursing Intervention for Chronic Pelvic Inflammatory Disease of the Damp-Heat and Blood Stasis Type

摘要: 目的：观察中医特色护理方案对慢性盆腔炎患者的疗效。方法：选取湿热瘀结型慢性盆腔炎患者200例，随机分配至试验组或对照组各100例。在21天的治疗期内，对照组接受常规护理，试验组患者接受中医特色护理。主要结局指标是临床疗效的总有效率。次要结局指标是中医主症评分、炎症因子水平相对于基线的变化。结果：试验组较对照组提高了临床疗效的总有效率(全分析集：93.0%和81.0%, P = 0.012；符合方案集94.7%和81.8%, P = 0.006)。相比于对照组，试验组中医主症评分、炎症因子(TNF-α, IL-6)水平较基线的降低幅度更大(P均<0.05)。结论：相比于常规护理，中医特色护理方案能够提高湿热瘀结型慢性盆腔炎的临床疗效，改善临床症状，抑制炎症反应。

Abstract: Objective: To evaluate the clinical effectiveness of a Traditional Chinese Medicine (TCM)-based nursing intervention in patients with chronic pelvic inflammatory disease (PID) of the damp-heat and blood stasis type. Methods: A total of 200 patients diagnosed with damp-heat and blood stasis type chronic PID were randomly assigned to either the intervention group or the control group (n = 100 per group). During a 21-day treatment period, the control group received standard nursing care, while the intervention group received a TCM-featured nursing program. The primary outcome was the overall clinical response rate. Secondary outcomes included changes from baseline in TCM syndrome scores and levels of inflammatory markers. Results: The intervention group demonstrated a significantly higher overall clinical response rate compared to the control group (full analysis set: 93.0% vs. 81.0%, P = 0.012; per-protocol set: 94.7% vs. 81.8%, P = 0.006). Moreover, the intervention group showed greater reductions in TCM syndrome scores and in serum levels of inflammatory cytokines (TNF-α, IL-6) relative to baseline, as compared to the control group (P < 0.05 for all). Conclusion: The TCM-based nursing intervention improved the clinical efficacy, alleviated clinical symptoms, and reduced inflammatory responses in patients with chronic PID of the damp-heat and blood stasis type, compared to standard care.