红花基因组学研究及应用
Research and Application of Genomics in Carthamus tinctorius
DOI: 10.12677/ojns.2025.135108, PDF,    科研立项经费支持
作者: 苏鲁方, 谭鑫雨, 胡涵冰, 陈 锐, 刘小云：江汉大学生命科学学院，汉江流域特色生物资源保护开发与利用工程技术研究中心，湖北 武汉
关键词: 红花；测序技术；基因组学；表观基因组学；Carthamus tinctorius； Sequencing Technology； Genomics； Epigenomics
摘要: 红花作为一种重要的经济作物，在食品、医药和工业等领域具有广泛应用。随着测序技术的快速发展，红花基因组学研究取得了显著进展。本文阐述了基于全基因组和表观基因组测序技术在红花基因组研究中的应用，包括全基因组测序(GWAS)、表观基因组测序(epiGWAS)和转录组测序等。整合GWAS、表观组、转录组与代谢组多组学，已挖掘脂肪酸合成(FAD2, FAB2)、类黄酮/羟基红花色素A合成(CHS, DFR, CtCGT1)、花色(YABBY, CYP450)及抗旱(CtWRKYs, CtSAMS1)等关键基因。未来，单细胞表观图谱、泛基因组及AI育种模型将加速高油、高黄酮、抗逆红花新品种创制，为分子育种与产业升级提供基因蓝图。
Abstract: Safflower (Carthamus tinctorius), as an important economic crop, has extensive applications in food, medicine, and industry. With the rapid development of sequencing technology, significant progress has been made in safflower genomics research. This article reviews the application of whole genome and epigenome sequencing technologies in safflower genomics research, including whole genome sequencing (GWAS), epigenome sequencing (epiGWAS), and transcriptome sequencing. By integrating GWAS, epigenome, transcriptome, and metabolome multi-omics, key genes involved in fatty acid synthesis (FAD2, FAB2), flavonoid/hydroxy safflower pigment A synthesis (CHS, DFR, CtCGT1), flower color (YABBY, CYP450), and drought resistance (CtWRKYs, CtSAMS1) have been identified. In the future, single-cell epigenomic maps, pan-genomes, and AI breeding models will accelerate the creation of new safflower varieties with high oil content, high flavonoid content, and stress resistance, providing a genetic blueprint for molecular breeding and industrial upgrading.
文章引用：苏鲁方, 谭鑫雨, 胡涵冰, 陈锐, 刘小云. 红花基因组学研究及应用[J]. 自然科学, 2025, 13(5): 1028-1036. https://doi.org/10.12677/ojns.2025.135108

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