尿AD7c-NTP在AD患者中的检测意义
The Significance of Detection Urine AD7c-NTP in Patients with Alzheimer’s Disease
DOI: 10.12677/acm.2025.1592639, PDF,   
作者: 沈 燕*, 张英杰：浙江新安国际医院老年科，浙江 嘉兴
关键词: 阿尔茨海默病；阿尔茨海默病相关神经丝蛋白；尿；AD； AD7c-NTP； Urine
摘要: 目的：本文通过检测AD7c-NTP在尿中的表达，探讨尿AD7c-NTP在AD患者中的检测意义。方法：本人将入院患者分为AD组以及非AD组，AD组通过MOCA分为重度AD组以及中度AD组。通过ELISA检测AD组、非AD组老年人的尿AD7c-NTP。结果：1) AD组尿AD7c-NTP的含量明显高于非AD组，P < 0.05。2) 重度痴呆组AD7c-NTP的含量明显高于中度痴呆组，中度痴呆组AD7c-NTP的含量明显高于轻度痴呆组，两组P均 < 0.05。结论：通过检测AD7c-NTP对AD的诊断以及评估AD的严重程度有一定的价值。
Abstract: Objective: This study through the detection of urine AD7c-NTP,discuss the significance of detection urinary AD7c-NTP in patients with Alzheimer’s disease. Methods: This study divided into patients with the group of AD and the group of normal. Through MOCA divided into patients with Alzheimer’s disease with serious group and medium group. Through ELISA detection all the pationts’ urine AD7c-NTP. Results: 1) Compared with the normal group, the levels of urine AD7c-NTP in AD group were significantly higher, (P < 0.05). 2) The content of AD7c-NTP in the severe dementia group was significantly higher than that in the moderate dementia group, and the content of AD7c-NTP in the moderate dementia group was significantly higher than that in the mild dementia group. Both groups had P < 0.05. Conclusion: The level of urine AD7c-NTP has helps of diagnosis AD and appraise the level of AD.
文章引用：沈燕, 张英杰. 尿AD7c-NTP在AD患者中的检测意义[J]. 临床医学进展, 2025, 15(9): 1413-1416. https://doi.org/10.12677/acm.2025.1592639

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