中医药修复肛周脓肿及肛瘘术后创面的信号通路研究进展
Research Progress on Signal Pathways for the Repair of Perianal Abscesses and Anal Fistulas Using Traditional Chinese Medicine
DOI: 10.12677/acm.2025.1592703, PDF,    科研立项经费支持
作者: 周子宁, 董淑翔, 张亚萍：成都中医药大学临床医学院，四川 成都；付 皓*：成都中医药大学附属医院肛肠科，四川 成都
关键词: 肛周脓肿；肛痿；手术；中医药疗法；创面愈合；信号通路；Anal Abscess； Anal Fistula； Surgery； TCM Therapy； Wound Healing； Signaling Pathways
摘要: 肛周脓肿及肛瘘发病率高，难以自愈，需手术治疗，术后创面如何减轻痛苦、快速愈合一直是研究热点。近年来，通过中医药促进术后创面愈合已成为主要方式。目前发现，中医药促进肛周脓肿及肛瘘术后创面愈合主要通过调控PI3K/Akt、Wnt/β-catenin、MAPK等信号通路。通过总结肛周脓肿及肛瘘术后应用中医药治疗患者创面愈合相关信号通路作用机制，旨在为中医药促进肛周脓肿及肛瘘术后患者创面生长的进一步研究提供依据。
Abstract: The incidence of perianal abscess and anal fistula is high, and it is difficult to heal itself, so it needs surgical treatment. How to relieve the pain and heal the wound quickly after operation has always been a research hotspot. In recent years, promoting postoperative wound healing through traditional Chinese medicine has become the main way. At present, it is found that traditional Chinese medicine can promote wound healing after perianal abscess and anal fistula mainly by regulating PI3K/Akt, Wnt/β-catenin, MAPK and other signal pathways. By summarizing the mechanism of signal pathway related to wound healing in patients with perianal abscess and anal fistula treated by traditional Chinese medicine, the purpose is to provide basis for further research on promoting wound growth in patients with perianal abscess and anal fistula treated by traditional Chinese medicine.
文章引用：周子宁, 董淑翔, 张亚萍, 付皓. 中医药修复肛周脓肿及肛瘘术后创面的信号通路研究进展[J]. 临床医学进展, 2025, 15(9): 1934-1939. https://doi.org/10.12677/acm.2025.1592703

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