毫火针留针联合针刺治疗PHN的研究进展
Research Progress on the Combined Use of Hao Fire Needle Retention and Acupuncture in the Treatment of Postherpetic Neuralgia
DOI: 10.12677/tcm.2025.1411737, PDF,   
作者: 刘淑毓:黑龙江中医药大学第一临床医学院,黑龙江 哈尔滨;王 珑*:黑龙江中医药大学附属第一医院针灸三科,黑龙江 哈尔滨
关键词: 带状疱疹后遗神经痛毫火针针刺综述Postherpetic Neuralgia Filiform Moxibustion Needle Acupuncture Overview
摘要: 带状疱疹后遗神经痛(Postherpetic Neuralgia, PHN)是带状疱疹(Herpes Zoster, HZ)最常见的后遗症,其症状表现为皮疹愈合后持续存在的剧烈疼痛,疼痛的性质多样、缠绵难愈,持续的疼痛导致患者长期生活质量下降。PHN病因复杂,当前西医治疗以药物为主,但常伴随不良反应且部分患者疗效不佳。近年来,毫火针留针联合针刺疗法作为一种中医特色外治法,在PHN的治疗中优势显著。该疗法集毫火针的温通散结、激发经气之功与针刺的疏通经络、调和气血之效于一体,能有效降低疼痛强度,改善患者睡眠障碍及焦虑。大量临床对照试验证实,火针联合针刺治疗方案在减轻疼痛、提高生活质量方面优于单一疗法或常规药物,且安全性较高,本综述探讨了该联合疗法的研究现状。
Abstract: Postherpetic Neuralgia (PHN) is the most common complication of Herpes Zoster (HZ). It is characterized by persistent, severe pain that remains after the skin rash has healed. The pain is diverse in nature, refractory, and leads to a long-term decline in patients’ quality of life. The etiology of PHN is complex. Current Western medical treatments primarily rely on medications, which are often associated with adverse effects and suboptimal efficacy in some patients. In recent years, filiform fire needle retention combined with acupuncture therapy, as a distinctive external treatment in Traditional Chinese Medicine, has shown significant advantages in the management of PHN. This integrated approach combines the warming, unblocking, dissipating nodulations, and stimulating meridian qi effects of the filiform fire needle with the channel-unblocking, qi-and-blood-regulating effects of acupuncture. It effectively reduces pain intensity and improves patients’ sleep disturbances and anxiety. Numerous randomized controlled trials have confirmed that the combined fire needle and acupuncture regimen is superior to monotherapy or conventional medication in alleviating pain and enhancing quality of life, with a favorable safety profile. This review explores the current research status of this combined therapeutic approach.
文章引用:刘淑毓, 王珑. 毫火针留针联合针刺治疗PHN的研究进展[J]. 中医学, 2025, 14(11): 5121-5126. https://doi.org/10.12677/tcm.2025.1411737

参考文献

[1] Cohen, J.I. (2013) Clinical Practice: Herpes Zoster. New England Journal of Medicine, 369, 255-263. [Google Scholar] [CrossRef] [PubMed]
[2] 于生元, 万有, 万琪, 等. 带状疱疹后神经痛诊疗中国专家共识[J]. 中国疼痛医学杂志, 2016, 22(3): 161-167.
[3] Li, Y., Jin, J., Kang, X. and Feng, Z. (2024) Identifying and Evaluating Biological Markers of Postherpetic Neuralgia: A Comprehensive Review. Pain and Therapy, 13, 1095-1117. [Google Scholar] [CrossRef] [PubMed]
[4] Drolet, M., Brisson, M., Schmader, K., Levin, M., Johnson, R., Oxman, M., et al. (2010) Predictors of Postherpetic Neuralgia among Patients with Herpes Zoster: A Prospective Study. The Journal of Pain, 11, 1211-1221. [Google Scholar] [CrossRef] [PubMed]
[5] Kawai, K., Yawn, B.P., Wollan, P. and Harpaz, R. (2016) Increasing Incidence of Herpes Zoster over a 60-Year Period from a Population-Based Study. Clinical Infectious Diseases, 63, 221-226. [Google Scholar] [CrossRef] [PubMed]
[6] 李元文, 王京军, 孙占学, 等. 从“络”探讨带状疱疹后遗神经痛的中医治疗[J]. 中医杂志, 2019, 60(8): 653-655.
[7] 曹东波. 益气化瘀通络方联合热敏灸治疗带状疱疹后遗神经痛的临床研究[J]. 中医药导报, 2018, 24(24): 123-126.
[8] 谢有权, 罗启年. 扶阳法治疗老年顽固性带状疱疹后遗神经痛12例[J]. 临床和实验医学杂志, 2007(6): 144.
[9] Johnson, R.W. and Rice, A.S.C. (2014) Postherpetic Neuralgia. New England Journal of Medicine, 371, 1526-1533. [Google Scholar] [CrossRef] [PubMed]
[10] Dworkin, R.H., et al. (2008) Recommendations for the Management of Herpes Zoster. Clinical Infectious Diseases, 47, 1-26.
[11] 贺普仁. 火针的机理及临床应用[J]. 中国中医药现代远程教育, 2004, 2(10): 20-24.
[12] 杨选频, 祁越. 师氏火针的刺法及其临床应用[J]. 实用中西医结合临床, 2004, 4(3): 29-30.
[13] 胡洁, 吴中朝. 火针齐刺留针治疗腰椎间盘突出症[J]. 吉林中医药, 2016, 36(9): 951-954.
[14] 沈钦彦. 火针留针治疗腰背肌筋膜炎的临床价值分析[J]. 中国处方药, 2015, 13(6): 70-71.
[15] 钟旋. 毫火针治疗肌筋膜炎的机制探讨[J]. 江西中医药, 2012, 43(6): 51-52.
[16] 李娟, 白伟杰, 郑永平, 等. 基于“以热引热”理论刘氏毫火针治疗疱疹期带状疱疹的疗效观察[J]. 时珍国医国药, 2022, 33(9): 2174-2176.
[17] 黎金凤, 王培, 李敏. 基于“温阳导滞理论”针刺联合火针治疗血瘀型带状疱疹后遗神经痛临床研究[J]. 针灸临床杂志, 2021, 37(4): 29-32.
[18] 杜鑫, 温小华, 刘迪生, 等. 火针疗法治疗作用及效应机制初探[J]. 针灸临床杂志, 2018, 34(9): 1-4.
[19] 朱光耀, 贾宁, 杨嘉恩, 等. 毫火针治疗带状疱疹后遗神经痛的临床疗效观察[J]. 智慧健康, 2023, 9(1): 170-173+177.
[20] 王凯, 李彬. 毫火针围刺配合循经取穴治疗肝胆火盛型带状疱疹后遗神经痛疗效观察[J]. 中国中医急症, 2022, 31(5): 854-857.
[21] 李颖, 文萃, 刘福水, 等. 毫火针点刺联合电针治疗带状疱疹后遗神经痛临床研究[J]. 针灸临床杂志, 2023, 39(8): 45-49.
[22] 王文炎, 梁凤霞. 火针疗法作用机理与临床应用的总结与探讨[C]//中国针灸学会. 2017世界针灸学术大会暨2017中国针灸学会年会论文集. 武汉: 湖北中医药大学针灸骨伤学院, 武汉市中医医院, 2017: 338-339.
[23] Zhao, Z. (2008) Neural Mechanism Underlying Acupuncture Analgesia. Progress in Neurobiology, 85, 355-375. [Google Scholar] [CrossRef] [PubMed]
[24] Han, J. (2003) Acupuncture: Neuropeptide Release Produced by Electrical Stimulation of Different Frequencies. Trends in Neurosciences, 26, 17-22. [Google Scholar] [CrossRef] [PubMed]
[25] 陈素艳, 李森林, 常晓彤. 迷走神经-胆碱能抗炎通路在糖尿病及其并发症中的作用[J]. 糖尿病新世界, 2022, 25(16): 189-194.
[26] Wei, X., Wang, L., Hua, J., Jin, X., Ji, F., Peng, K., et al. (2021) Inhibiting BDNF/TrkB.T1 Receptor Improves Resiniferatoxin-Induced Postherpetic Neuralgia through Decreasing ASIC3 Signaling in Dorsal Root Ganglia. Journal of Neuroinflammation, 18, Article No. 96. [Google Scholar] [CrossRef] [PubMed]
[27] 孙莹, 刘晶, 刘雅婷, 等. 毫火针点刺联合针刺治疗带状疱疹后遗神经痛的临床观察[J]. 中国民间疗法, 2018, 26(4): 43-44.
[28] Tatsumi, E., Yamanaka, H., Kobayashi, K., Yagi, H., Sakagami, M. and Noguchi, K. (2015) Rhoa/Rock Pathway Mediates P38 MAPK Activation and Morphological Changes Downstream of P2Y12/13 Receptors in Spinal Microglia in Neuropathic Pain. Glia, 63, 216-228. [Google Scholar] [CrossRef] [PubMed]