癌症患者经济毒性研究现状与进展

Status and Progress of Financial Toxicity Research in Cancer Patients

摘要: 癌症作为全球重要公共卫生问题，其诊断与治疗引发的经济毒性严重影响患者及家庭的经济与生活质量。通过综述国内外关于癌症患者经济毒性的研究进展，本文重点探讨其核心概念、常用评估工具、影响因素及多层次干预策略。研究发现，经济毒性评估工具的开发与验证取得显著进展，但国内研究仍处于初期，亟需开发本土化工具并探索符合国情的前瞻性干预措施。此外，现有研究揭示了治疗方式及医疗保险覆盖不足等因素对经济毒性的显著影响，而财务导航模式、成本沟通等干预策略展现出缓解经济负担的潜力。本综述为未来研究提供理论参考，并为政策制定和临床实践优化提供方向，以期减轻癌症患者的经济毒性，改善其生活质量。

Abstract: Cancer, a significant global public health issue, induces financial toxicity consequent to its diagnosis and treatment processes, which exerts a substantial influence on the economic conditions and quality of life of patients and their families. This article undertakes a comprehensive review of the research progress in the field of financial toxicity among cancer patients both at home and abroad. The focus lies in elucidating its core concepts, commonly employed assessment tools, influencing factors, and multi-level intervention strategies. It has been observed that substantial advancements have been made in the development and validation of financial toxicity assessment tools. However, the domestic research in this regard is still in its nascent phase, thereby urgently necessitating the development of localized tools and the exploration of prospective intervention measures that are congruent with the national circumstances. Moreover, extant research has revealed that factors such as treatment modalities and insufficient medical insurance coverage have a significant impact on financial toxicity. Concurrently, intervention strategies, including financial navigation models and cost communication, have manifested the potential to alleviate the financial burden. This review provides a theoretical reference for future research and offers guidelines for policy formulation and the optimization of clinical practice, with the anticipation of mitigating the financial toxicity of cancer patients and ameliorating their quality of life.