中性粒细胞百分比与白蛋白的比值与新发心力衰竭的研究进展
Research Progress on the Ratio of Neutrophil Percentage to Albumin in Newly Diagnosed Heart Failure
DOI: 10.12677/acm.2025.15123478, PDF,   
作者: 邢平川, 陈依璠, 朱诗源, 雷 涛：华北理工大学研究生院，河北 唐山；华北理工大学附属医院心内二科，河北 唐山；王志军*：华北理工大学附属医院心内二科，河北 唐山
关键词: 心力衰竭；中性粒细胞；白蛋白；中性粒细胞百分比与白蛋白比值；Heart Failure； Neutrophils； Albumin； Ratio of Neutrophil Percentage to Albumin
摘要: 心力衰竭是一种发病率高、病死率高、社会经济负担重的各种心脏结构和(或)功能异常改变所致的心血管性疾病，心力衰竭是老年人的常见病，其社会经济负担重，是目前世界范围内的重大公共卫生问题，已成为我国医疗保健的一个不可忽视的问题。中性粒细胞产生炎症介质，在介导炎症反应中起重要作用。白蛋白作为一种至关重要的调节蛋白，有抗炎、抗氧化等作用，可参与多种心血管疾病。而中性粒细胞百分比与白蛋白的比值，以中性粒细胞百分比分子除以血清白蛋白浓度计算，可以放大这两个可获得的评价参数的变化，为每位心力衰竭患者提供快速的风险评估，以便为治疗策略和医疗资源分配做出更精确的决策。本文就中性粒细胞、白蛋白以及中性粒细胞百分比与白蛋白的比值与新发心力衰竭的相关研究进展展开作一综述。
Abstract: Heart failure is a cardiovascular disease caused by various structural and/or functional abnormalities of the heart, characterized by high incidence, high mortality, and a heavy socioeconomic burden. It has become a significant issue in healthcare in China. Neutrophils produce inflammatory mediators and play an important role in mediating inflammatory responses. Albumin, as a crucial regulatory protein, participates in anti-inflammatory and antioxidant functions and is involved in various cardiovascular diseases. The ratio of neutrophil percentage to albumin (NAR), calculated by dividing the neutrophil percentage by the serum albumin concentration, can amplify changes in these two readily available parameters, providing rapid risk assessment for each heart failure patient and enabling more precise decisions regarding treatment strategies and healthcare resource allocation. This article reviews the research progress on neutrophils, albumin, and the ratio of neutrophil percentage to albumin in relation to new-onset heart failure.
文章引用：邢平川, 陈依璠, 朱诗源, 雷涛, 王志军. 中性粒细胞百分比与白蛋白的比值与新发心力衰竭的研究进展[J]. 临床医学进展, 2025, 15(12): 847-852. https://doi.org/10.12677/acm.2025.15123478

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