基于脏腑体系辨证论治血管性认知障碍的研究进展
Research Progress on the Treatment of Vascular Cognitive Impairment Based on Visceral Theory and Syndrome Differentiation
摘要: 血管性认知障碍(VCI)由脑血管病变及其危险因素引发的认知功能损害综合征，该病起病隐匿，发病率高，远期危害大。目前VCI尚无特异性治疗，传统医学在治疗VCI中展现出独特优势。VCI病机为本虚标实，虚实夹杂。现基于脏腑体系，系统梳理中医辨证论治VCI的理法方药，结合现代医学的病理机制与干预靶点，阐明“肾–脑髓”“心脾–代谢免疫”“肝–神经炎症”“肺肠–脑肠轴”等中西医协同作用网络。通过整合临床研究与基础实验证据，提出多靶点干预策略，以期为VCI的精准诊疗提供新思路，推动中医药现代化与国际转化。
Abstract: Vascular cognitive impairment (VCI) is a cognitive impairment syndrome caused by cerebrovascular disease and its risk factors. The disease has a hidden onset, a high incidence rate and great long-term harm. At present, there is no specific treatment for VCI, and traditional medicine has shown unique advantages in treating VCI. A combination of deficiency and excess characterises the pathogenesis of VCI. Based on the theory of organs and viscera, this paper systematically sorts out the principles, methods, and prescriptions of traditional Chinese medicine for treating VCI through syndrome differentiation. Combined with the pathological mechanisms and intervention targets of modern medicine, it elucidates the synergistic network of Chinese and Western medicine, such as “kidney brain marrow” “heart spleen metabolic immunity” “liver neuroinflammation” and “lung gut brain gut axis”. By integrating clinical research and basic experimental evidence, a multi-target intervention strategy is proposed to provide new ideas for the precise diagnosis and treatment of VCI, and to promote the modernisation and international transformation of traditional Chinese medicine.
文章引用：姚颖慧, 刘云龙, 李广顺, 樊召霞, 樊晓靖. 基于脏腑体系辨证论治血管性认知障碍的研究进展[J]. 临床医学进展, 2025, 15(12): 853-861. https://doi.org/10.12677/acm.2025.15123479

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