洛芬待因联合加巴喷丁治疗重型带状疱疹临床观察

Clinical Observation of Combined with Ibuprofen and Codeine Phosphate and Gabapentin in the Treatment of Severe Herpes Zoster

摘要: 目的：探讨洛芬待因片联合加巴喷丁胶囊治疗重型带状疱疹的临床效果。方法：全部病例随机分成两组：A组(观察组) 36例：采用洛芬待因片，加巴喷丁胶囊，伐昔洛韦片，5%复方利多卡因乳膏治疗。B组(对照组) 36例：采用尼美舒利缓释片，伐昔洛韦片，5%复方利多卡因乳膏治疗。结果：两组疼痛消退情况的比较：A组总有效率为88.89%，B组总有效率为58.33%。两组总有效率经χ²检验，χ² = 8.65，P < 0.01，差异有统计学意义，说明A组疼痛消退情况优于B组。结论：洛芬待因片联合加巴喷丁胶囊治疗重型带状疱疹取得较好疗效，值得临床推广。

Abstract: Objective: To investigate the clinical efficacy of Ibuprofen and Codeine Phosphate Tablets combined with Gabapentin capsules in the treatment of severe herpes zoster. Methods: All cases were randomly divided into two groups: group A (observation group) with 36 cases: treated with Ibuprofen and Codeine Phosphate Tablets, Gabapentin capsules, Valaciclovir tablets and 5% compound Lidocaine cream. 36 cases in group B (control group) were treated with Nimesulide sustained-release tablets, valaciclovir tablets and 5% compound Lidocaine cream. Results: Comparison of pain relief between the two groups: the total effective rate of group A was 88.89%, and that of group B was 58.33%. The total effective rate of the two groups was tested by χ², χ² = 8.65, P < 0.01, the difference was statistically significant, indicating that the pain relief in group A was better than that in group B. Conclusion: Ibuprofen and Codeine Phosphate Tablets combined with Gabapentin capsule in the treatment of severe herpes zoster achieved a good curative effect, worthy of clinical promotion.