腹腔镜胆囊切除手术入路研究现状及进展
Research Status and Advances in Surgical Approaches for Laparoscopic Cholecystectomy
摘要: 胆囊良性疾病是临床常见的消化系统疾病,其发病率伴随生活方式的改变呈上升趋势。腹腔镜胆囊切除术(Laparoscopic Cholecystectomy, LC)凭借其微创优势,已成为该病的首选治疗方式。然而,胆道损伤作为LC最严重的并发症,仍严重威胁患者预后,其发生主要与胆囊三角区解剖结构辨识困难有关。手术入路作为LC操作的核心环节,直接关系解剖视野的清晰度、关键结构的辨识准确性及整体手术安全性,合理选择入路对降低并发症风险具有关键意义。本文系统梳理近年国内外相关研究,围绕“关键安全视野(CVS)”与“退出策略(Bailout Procedure)”两大核心安全理念,总结LC常用手术入路的技术特点与临床应用,包括经典的胆囊前三角入路、胆囊后三角入路,创新的“V”形、“Y”形及“T”形解剖入路,以及适用于复杂病例的胆囊底入路、壶腹入路与胆囊内入路等。进一步探讨不同入路在实现CVS或作为Bailout策略中的角色与选择逻辑,对规范手术操作、优化治疗策略及改善患者预后具有重要临床价值。
Abstract: Benign gallbladder diseases are common clinical disorders of the digestive system, with an increasing incidence linked to changes in lifestyle. Laparoscopic cholecystectomy (LC) has become the preferred treatment due to its minimally invasive advantages. However, bile duct injury, the most severe complication of LC, remains a significant threat to patient outcomes, primarily associated with difficulties in identifying anatomical structures within the Calot’s triangle. The surgical approach, as a core element of LC, directly affects the clarity of the anatomical field, the accurate identification of critical structures, and overall procedural safety. Therefore, the appropriate selection of an approach is crucial for reducing complication risks. This review systematically summarizes recent domestic and international studies, focusing on the core safety concepts of the Critical View of Safety (CVS) and Bailout Procedures. It outlines the technical characteristics and clinical applications of common LC surgical approaches, including the classic anterior and posterior cystic triangle approaches, innovative anatomical approaches such as the “V”, “Y”, and “T” shaped dissections, as well as specialized approaches for complex cases like the fundus-first, infundibular, and intracorporeal approaches. Furthermore, it explores the role and selection rationale of different approaches in achieving CVS or serving as a Bailout strategy, highlighting significant clinical value for standardizing operative procedures, optimizing treatment plans, and improving patient outcomes.
文章引用:万柏江, 刘立民, 刘卓. 腹腔镜胆囊切除手术入路研究现状及进展[J]. 外科, 2025, 14(4): 95-102. https://doi.org/10.12677/hjs.2025.144012

参考文献

[1] 杨健, 吴忠均, 廖锐. 胆囊良性疾病的诊断与治疗研究进展[J]. 中华肝胆外科杂志, 2024, 30(5): 395-400.
[2] Morikawa, T., Akada, M., Shimizu, K., Nishida, Y., Izai, J., Kajioka, H., et al. (2023) Current Status and Therapeutic Strategy of Acute Acalculous Cholecystitis: Japanese Nationwide Survey in the Era of the Tokyo Guidelines. Journal of Hepato-Biliary-Pancreatic Sciences, 31, 162-172. [Google Scholar] [CrossRef] [PubMed]
[3] Malla, S.N., Rahman Dar, W.U., Bashir, H., Malik, I.A. and Lone, B.A. (2025) Critical View of Safety in Laparoscopic Cholecystectomy: A Prospective, Observational Study. International Journal of Human and Health Sciences (IJHHS), 9, 48-52. [Google Scholar] [CrossRef
[4] Chooklin, S.M. and Chuklin, S.S. (2024) How to Prevent Complications in Laparoscopic Cholecystectomy: A Critical View of Safety. Emergency Medicine, 20, 376-387. [Google Scholar] [CrossRef
[5] Meziani, H., Seoud, Z., Benblidia, A., Khelif, A., Kara Ahmed, M. and Mechrouk, A. (2024) Is Conversion the Only Itinerary to Peace with “Hostile” Laparoscopic Cholecystectomy? Batna Journal of Medical Sciences (BJMS), 11, 392-395. [Google Scholar] [CrossRef
[6] Hong, J.S. and Nair, R. (2025) Strategies to Adopt in a Challenging Laparoscopic Cholecystectomy. Journal of Surgical Specialties and Rural Practice, 6, 63-69. [Google Scholar] [CrossRef
[7] Broderick, R.C., Lee, A.M., Cheverie, J.N., Zhao, B., Blitzer, R.R., Patel, R.J., et al. (2020) Fluorescent Cholangiography Significantly Improves Patient Outcomes for Laparoscopic Cholecystectomy. Surgical Endoscopy, 35, 5729-5739. [Google Scholar] [CrossRef] [PubMed]
[8] 牛四明. 不同Calot三角解剖入路腹腔镜胆囊切除术治疗胆囊结石伴慢性胆囊炎患者疗效对比分析[J]. 实用肝脏病杂志, 2018, 21(3): 447-450.
[9] 郑峰, 李彦荣, 罗卫军, 等. 经胆囊后三角入路和经胆囊三角入路腹腔镜胆囊切除术治疗胆囊结石伴慢性胆囊炎患者疗效及对血清炎症因子的影响[J]. 实用肝脏病杂志, 2023, 26(4): 580-583.
[10] 陈宏存, 汤大纬, 张军, 等. Rouviere沟为导向的胆囊三角解剖法在困难腹腔镜胆囊切除术中的应用[J]. 肝胆外科杂志, 2019, 27(2): 128-131.
[11] 熊秋生, 邹征嵘. Mirizzi综合征45例诊治体会[J]. 肝胆胰外科杂志, 2022, 34(10): 628-629.
[12] 陈光彬, 刘丹峰, 章新桥, 等. Rouviere沟引导的胆囊后三角入路在预防腹腔镜胆囊切除术中胆管损伤的作用[J]. 中华普通外科杂志, 2018, 33(2): 101-104.
[13] 朱培红. 胆囊后三角入路刮吸法腹腔镜胆囊切除术治疗急性结石性胆囊炎患者的疗效评价[J]. 实用中西医结合临床, 2021, 21(9): 26-27.
[14] 毕洁领, 刘美宏, 宋国庆. Rouviere沟引导定向联合胆囊后三角入路腹腔镜胆囊切除术治疗胆囊良性疾病研究[J]. 实用肝脏病杂志, 2020, 23(2): 288-291.
[15] 安宏超, 徐宏征, 崔宏力. 胆囊后三角入路LC治疗急性胆囊炎的效果分析[J]. 肝胆胰外科杂志, 2024, 36(2): 100-103.
[16] 尚志文. 后三角优先入路在急性结石性胆囊炎LC术中的临床效果观察[J]. 肝胆外科杂志, 2018, 26(4): 296-298.
[17] 魏松伟, 张景春. 胆囊三角“V”字形解剖入路在腹腔镜下复杂胆囊切除术患者中的应用效果[J]. 临床医学研究与实践, 2023, 8(24): 78-81.
[18] 曾碧城, 丁胜文, 骆菁, 黄楚忠, 方忠荣, 谢健, 殷容暖, 尹锡洲. V字形解剖入路在腹腔镜胆囊切除术中的应用[J]. 现代诊断与治疗, 2017, 28(4): 717-718.
[19] 辛海贝, 张含, 张存圳, 等. 胆囊管浆膜Y形入路在腹腔镜胆囊切除术中的应用[J]. 中国现代手术学杂志, 2021, 25(4): 251-254.
[20] 汪明术. T型入路及动脉先行解剖胆囊三角在腹腔镜胆囊切除术中的应用[J]. 肝胆外科杂志, 2023, 31(6): 453-456, 480.
[21] 陆磊, 金旭文, 陆峰. 逆行胆囊切除术在腹腔镜胆囊切除术中的应用[J]. 中国微创外科杂志, 2014, 14(2): 180-181.
[22] de’Angelis, N., Catena, F., Memeo, R., Coccolini, F., Martínez-Pérez, A., Romeo, O.M., et al. (2021) 2020 WSES Guidelines for the Detection and Management of Bile Duct Injury during Cholecystectomy. World Journal of Emergency Surgery, 16, Article No. 30. [Google Scholar] [CrossRef] [PubMed]
[23] Jalal Namq, A., Muhammed Dewana, A., Saeed Ahmed, B., Ahmed Aziz, S. and Shalli, K. (2024) Evaluation of Fundus First Laparoscopic Cholecystectomy in an Obscured Calot Triangle: Outcomes. Diyala Journal of Medicine, 27, 1-11. [Google Scholar] [CrossRef
[24] Garzali, I.U., Aburumman, A., Alsardia, Y., Alabdallat, B., Wraikat, S. and Aloun, A. (2022) Is Fundus First Laparoscopic Cholecystectomy a Better Option than Conventional Laparoscopic Cholecystectomy for Difficult Cholecystectomy? A Systematic Review and Meta-Analysis. Updates in Surgery, 74, 1797-1803. [Google Scholar] [CrossRef] [PubMed]
[25] Strasberg, S.M., Eagon, C.J. and Drebin, J.A. (2000) The “Hidden Cystic Duct” Syndrome and the Infundibular Technique of Laparoscopic Cholecystectomy—The Danger of the False Infundibulum. Journal of the American College of Surgeons, 191, 661-667. [Google Scholar] [CrossRef] [PubMed]
[26] Cengiz, Y., Lund, M., Jänes, A., Lundell, L., Sandblom, G. and Israelsson, L. (2019) Fundus First as the Standard Technique for Laparoscopic Cholecystectomy. Scientific Reports, 9, Article No. 18736. [Google Scholar] [CrossRef] [PubMed]
[27] Edergren, Å., Sandblom, G., Franko, M., Agustsson, T., Cengiz, Y. and Jaafar, G. (2024) Safety of Cholecystectomy Performed by Surgeons Who Prefer Fundus First versus Surgeons Who Prefer a Standard Laparoscopic Approach. Surgery Open Science, 19, 141-145. [Google Scholar] [CrossRef] [PubMed]
[28] 黄志明, 周栋. 壶腹入路腹腔镜胆囊切除术预防胆管损伤的体会[J]. 肝胆胰外科杂志, 2015, 27(4): 334-335.
[29] 张好春, 钱家成, 王文友, 等. 壶腹部远端入路法预防腹腔镜胆囊切除术相关胆管损伤[J]. 肝胆胰外科杂志, 2011, 23(4): 320-322.
[30] 闫北平, 郑圣保, 国维克, 等. 胆囊切开引导胆囊管在复杂胆囊切除术中的应用体会[J]. 海南医学, 2014(14): 2145-2146, 2147.
[31] 王毅, 刘杰. 腹腔镜困难胆囊切除术的手术策略分析[J]. 腹腔镜外科杂志, 2021, 26(9): 683-686, 690.
[32] 何其勇, 王双. 胆囊剖开法胆囊切除术13例临床报告[J]. 黑龙江医药科学, 2001, 24(2): 77.
[33] 武成旭, 张伟辉. 困难性腹腔镜胆囊切除术的技巧[J]. 中国现代普通外科进展, 2022, 25(3): 246-249.