胃癌骨髓转移1例并文献复习
A Case of Gastric Cancer with Bone Marrow Metastasis and Literature Review
DOI: 10.12677/acm.2025.15123657, PDF,   
作者: 梁依琳, 王 亮*, 王 娜:暨南大学第一临床医学院,广东 广州;暨南大学附属第一医院肿瘤科,广东 广州
关键词: 胃癌骨转移骨髓转移Gastric Cancer Bone Metastasis Bone Marrow Metastasis
摘要: 骨髓转移泛指原发于非造血组织的恶性肿瘤细胞经血行播散或淋巴道转移至骨髓的总称。胃癌是常见的消化道肿瘤,主要转移部位为肝和肺,骨转移相对少见,骨髓转移是骨转移的一种亚型,发生率更低,目前多见于病例报道。胃癌骨髓转移患者预后非常差。为了加强临床医生对本病的认识,本文报道1例胃癌骨髓转移病例,并复习相关文献。
Abstract: Bone marrow metastasis generally refers to the general term for malignant tumor cells originating from non-hematopoietic tissues that spread to the bone marrow via hematogenous dissemination or lymphatic metastasis. Gastric cancer is a common gastrointestinal tumor, with the main metastatic sites being the liver and lungs. Bone metastasis is relatively rare, and bone marrow metastasis, as a subtype of bone metastasis, has an even lower incidence rate, which is currently mostly reported in case studies. The prognosis of patients with gastric cancer and bone marrow metastasis is extremely poor. To enhance clinicians’ understanding of this disease, this article reports one case of gastric cancer with bone marrow metastasis and reviews the relevant literature.
文章引用:梁依琳, 王亮, 王娜. 胃癌骨髓转移1例并文献复习[J]. 临床医学进展, 2025, 15(12): 2309-2313. https://doi.org/10.12677/acm.2025.15123657

参考文献

[1] Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R.L., Soerjomataram, I., et al. (2024) Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 74, 229-263. [Google Scholar] [CrossRef] [PubMed]
[2] Kim, H.S., Yi, S.Y., Jun, H.J., Lee, J., Park, J.O., Park, Y.S., et al. (2007) Clinical Outcome of Gastric Cancer Patients with Bone Marrow Metastases. Oncology, 73, 192-197. [Google Scholar] [CrossRef] [PubMed]
[3] Kwon, J.Y., Yun, J., Kim, H.J., Kim, K., Kim, S., Lee, S., et al. (2011) Clinical Outcome of Gastric Cancer Patients with Bone Marrow Metastases. Cancer Research and Treatment, 43, 244-249. [Google Scholar] [CrossRef] [PubMed]
[4] Turkoz, F.P., Solak, M., Kilickap, S., Ulas, A., Esbah, O., Oksuzoglu, B., et al. (2014) Bone Metastasis from Gastric Cancer: The Incidence, Clinicopathological Features, and Influence on Survival. Journal of Gastric Cancer, 14, Article 164. [Google Scholar] [CrossRef] [PubMed]
[5] Kobayashi, M., Okabayashi, T., Sano, T. and Araki, K. (2005) Metastatic Bone Cancer as a Recurrence of Early Gastric Cancer—Characteristics and Possible Mechanisms. World Journal of Gastroenterology, 11, 5587-5591.
[6] Yumoto, K., Eber, M.R., Berry, J.E., Taichman, R.S. and Shiozawa, Y. (2014) Molecular Pathways: Niches in Metastatic Dormancy. Clinical Cancer Research, 20, 3384-3389. [Google Scholar] [CrossRef] [PubMed]
[7] Iguchi, H. (2015) Recent Aspects for Disseminated Carcinomatosis of the Bone Marrow Associated with Gastric Cancer: What Has Been Done for the Past, and What Will Be Needed in Future? World Journal of Gastroenterology, 21, Article 12249. [Google Scholar] [CrossRef] [PubMed]