基于“态靶理论”探析代谢综合征心脑血管疾病的病机演变和治疗策略

Exploring the Pathogenesis Evolution and Therapeutic Strategies of Cardiovascular and Cerebrovascular Diseases in Metabolic Syndrome Based on the “State-Target Theory”

摘要: “态靶理论”将中医整体观与西医靶向治疗思想有机融合，为全面理解疾病发生发展提供了全新视角。代谢综合征包含的多种代谢异常如高血压、高血脂和高血糖，均为心脑血管疾病的重要危险因素。依据中医理论，代谢综合征可归属于“膏浊”范畴，其伴发心脑血管疾病的过程可分为三个阶段：“病精微物质”“病脉络”和“病脏腑”，分别对应“脉浊”“脉坚”和“脉损”三个病理环节。基于“态靶理论”，本文探讨了代谢综合征伴发心脑血管疾病的病理演变、体质易感性及治疗策略，以期为临床治疗提供理论基础。

Abstract: The “State-Target Theory” integrates the holistic view of Chinese medicine with the idea of targeted treatment of Western medicine, providing a new perspective for a comprehensive understanding of the development of diseases. Metabolic syndrome encompasses a variety of metabolic abnormalities such as hypertension, hyperlipidemia, and hyperglycemia, all of which are important risk factors for cardiovascular and cerebrovascular disease. According to Chinese medicine theory, metabolic syndrome can be attributed to the category of “creamy turbidity”, and the process of cardiovascular and cerebrovascular diseases can be divided into three stages: “disease essence and micro-matter”, “disease veins and channels” and “disease organs”, corresponding to the three pathological links of “turbid veins”, “vein firmness” and “vein damage” respectively. Based on the “state-target theory”, this paper discusses the pathological evolution, physical susceptibility and therapeutic strategies of metabolic syndrome associated with cardiovascular and cerebrovascular diseases, with a view to providing a theoretical basis for clinical treatment.