不同波长激光光凝对糖尿病性视网膜病变患者黄斑水肿吸收及视功能的疗效观察

Efficacy of Different Wavelength Laser Photocoagulation on Macular Edema Absorption and Visual Function in Diabetic Retinopathy Patients

摘要: 目的：比较532 nm绿色激光与577 nm黄激光光凝治疗中度非增殖期糖尿病视网膜病变(DR)合并黄斑水肿(DME)的临床疗效。方法：纳入2023年2月至2025年1月收治的134例DME患者，随机分为532 nm组67例和577 nm组67例，两组均行局灶/格栅光凝。结果：577 nm组黄斑厚度降幅显著大于532 nm组；577 nm组BCVA提升优于532 nm组，577 nm组并发症发生率低于532 nm组。结论：577 nm黄激光较532 nm绿色激光更有效促进黄斑水肿吸收，改善视功能且安全性更高，波长选择性光凝可为DR个体化治疗提供新策略。

Abstract: Objective: To compare the clinical efficacy of 532-nm green laser versus 577-nm yellow laser photocoagulation in moderate non-proliferative diabetic retinopathy (DR) patients with diabetic macular edema (DME). Methods: A total of 134 DME patients admitted between February 2023 and January 2025 were enrolled and randomized into a 532-nm group (67 cases) and a 577-nm group (67 cases). Both groups underwent focal/grid photocoagulation. Results: The reduction in macular thickness was significantly greater in the 577-nm group than in the 532-nm group. Best-corrected visual acuity (BCVA) improvement was superior in the 577-nm group, and the complication rate was lower in the 577-nm group. Conclusion: Compared to 532-nm green laser, 577-nm yellow laser more effectively promotes macular edema absorption, improves visual function, and demonstrates higher safety. Wavelength-selective photocoagulation may offer a novel strategy for individualized DR treatment.