新鲜冰冻血浆逆转全身麻醉后米库氯铵所致苏醒延迟一例

Reversal of Mivacurium-Induced Delayed Awakening after General Anesthesia with Fresh Frozen Plasma: A Case Report

摘要: 全麻后苏醒延迟是麻醉实践中常见的临床问题，主要指全身麻醉结束后患者超过预期时间仍未恢复意识且不能对言语或刺激等作出有思维的回答或动作。其发生机制复杂多样，在临床工作中诊治困难，且与患者术后恢复密切相关。苏醒延迟延长患者在麻醉恢复室(PACU)的监护时间以及机械通气时间，增加术后各种并发症发生的风险，延缓患者术后康复，增加患者的术后住院时间和住院费用，加重患者的经济及健康负担。因此针对术后苏醒延迟发生的危险因素采取必要预防措施具有重要意义。厘清全麻患者术后苏醒延迟发生情况以及其危险因素，能够为全麻患者术后苏醒延迟的防治提供参考依据。现将临床处理全麻后苏醒延迟1例病例报道如下，以提升麻醉医师对该情况的综合处置能力。

Abstract: Delayed awakening after general anesthesia is a common clinical issue in anesthetic practice, primarily referring to the failure of patients to regain consciousness and respond meaningfully to verbal commands or stimuli beyond the expected timeframe following the conclusion of general anesthesia. Its underlying mechanisms are complex and varied, posing diagnostic and therapeutic challenges in clinical practice, and it is closely associated with patient postoperative recovery. Delayed awakening prolongs patients’ monitoring time in the Post-Anesthesia Care Unit (PACU) and the duration of mechanical ventilation, increases the risk of various postoperative complications, delays postoperative rehabilitation, extends hospital stay and raises hospitalization costs, thereby imposing greater economic and health burdens on patients. Therefore, it is of significant importance to adopt necessary preventive measures targeting the risk factors associated with postoperative delayed awakening. Clarifying the incidence and risk factors of delayed awakening in patients after general anesthesia can provide valuable insights for its prevention and management. We thereby present a case report on the clinical management of delayed awakening after general anesthesia to enhance anesthesiologists’ comprehensive competency in handling this condition.