心肌活检诊断DCM规范联合治疗改善 心功能1例

Improvement of Cardiac Function with Standardized Combined Therapy in a Case of Dilated Cardiomyopathy Diagnosed by Myocardial Biopsy

摘要: 目的：探讨心肌活检诊断扩张型心肌病(Dilated Cardiomyopathy, DCM)且规范联合应用抗心衰治疗在患者中的临床疗效及应用价值。方法：回顾性分析1例28岁男性以急性心衰为主要临床表现的DCM患者的临床资料、心肌活检病理结果及治疗随访过程。结果：规范使用抗心衰五联药物治疗后，患者左心室内径回缩，LVEF显著提升并维持于正常范围。结论：体现DCM精准诊断、规范联合治疗及长期随访的重要性，为临床类似病例的诊疗提供了参考。

Abstract: Objective: To explore the clinical efficacy and application value of endomyocardial biopsy in the diagnosis of dilated cardiomyopathy (DCM) combined with standardized anti-heart failure therapy in patients. Methods: The clinical data, pathological results of myocardial biopsy, treatment and follow-up process of a 28-year-old male DCM patient with acute heart failure as the main clinical manifestation were retrospectively analyzed. Results: After standardized treatment with the five-drug combination for anti-heart failure, the patient’s left ventricular internal diameter regressed, and the left ventricular ejection fraction (LVEF) increased significantly and remained within the normal range. Conclusion: This case demonstrates the importance of accurate diagnosis, standardized combined therapy and long-term follow-up for DCM, and provides a reference for the diagnosis and treatment of similar clinical cases.