基于“虚气流滞”理论论治反复发作性尿路 感染

Treatment of Recurrent Urethral Infection Based on the Theory of “Deficient-Qi Induced Stagnation”

摘要: 反复发作性尿路感染(RUTI)是泌尿外科及肾内科的临床难点，抗生素耐药及停药复发问题突出。探索中医药防治该病的有效理论和方法，对于减少抗生素使用、降低复发率及改善患者生活质量具有实际临床价值。本文基于“虚气流滞”理论，认为RUTI以脾肾虚弱为本，膀胱湿热为标，虚是发病基础，滞是病理产物也是致病因素，是虚气与留滞共同作用的恶性循环。“虚气流滞”动态地解释了RUTI本虚标实，虚实夹杂的病理状态，充分解释了RUTI患者由缓解期发展到急性期的过程，使RUTI的核心病机、病理进程更加清晰明了，以期为中医药治疗RUTI开启新思路，改善患者生活质量。

Abstract: Recurrent Urinary Tract Infections (RUTI) pose significant clinical challenges in urology and nephrology, with antibiotic resistance and recurrence after discontinuation being prominent issues. Exploring effective theories and methods for preventing and treating this condition using traditional Chinese medicine holds practical clinical value in reducing antibiotic use, lowering recurrence rates, and improving patients’ quality of life. This paper proposes that RUTI fundamentally stems from spleen-kidney deficiency, with bladder damp-heat manifesting as the secondary symptom. Deficiency forms the foundation of the disease, while stagnation serves as both a pathological product and a causative factor, creating a vicious cycle driven by the combined effects of “Deficient-Qi Induced Stagnation”. This dynamic interpretation of “Deficient-Qi Induced Stagnation” elucidates RUTI’s pathological state of underlying deficiency with superimposed excess, fully explaining the progression from remission to acute phases. It clarifies RUTI’s core pathogenesis and disease progression, aiming to pioneer new approaches for TCM treatment and enhance patient quality of life.