高危型HPV感染临床转归相关因素研究进展
Advances in Research on Related Factors of Clinical Outcomes of High-Risk Human Papillomavirus (HR-HPV) Infection
摘要: 目前高危型人乳头瘤病毒(HR-HPV)已被全球公认为导致宫颈癌的首要生物学因素。尽管绝大多数HPV感染为一过性自限性过程，但其持续感染在宫颈癌的发生、发展过程中发挥关键作用。近年来，国内外学者已聚焦于影响高危型HPV转归的相关因素研究，明确了高危型HPV感染后的转归受多维度因素调控。本文旨在对这些影响因素进行综述，为精准识别HPV持续感染高危人群、有效预防宫颈癌前病变提供参考依据。
Abstract: At present, high-risk human papillomavirus (HR-HPV) has been globally recognized as the primary biological factor leading to cervical cancer. Although the vast majority of HPV infections are transient and self-limiting, persistent infection plays a key role in the occurrence and development of cervical cancer. In recent years, scholars at home and abroad have focused on the research of factors affecting the outcome of high-risk HPV infection, and it has been clarified that the outcome of high-risk HPV infection is regulated by multi-dimensional factors. This article aims to review these influencing factors, so as to provide a reference for accurately identifying high-risk groups of persistent HPV infection and effectively preventing cervical precancerous lesions.
文章引用：苏庭婷, 常淑芳. 高危型HPV感染临床转归相关因素研究进展[J]. 临床医学进展, 2026, 16(2): 2329-2335. https://doi.org/10.12677/acm.2026.162635

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