直肠前切除综合征的研究进展
Research Progress on Anterior Rectal Resection Syndrome
DOI: 10.12677/acm.2026.162664, PDF,   
作者: 黄晓嵩, 吴雪松*：昆明医科大学附属第二医院胃肠外科一病区，云南 昆明
关键词: 保肛手术；低位前切除综合征；直肠癌；Sphincter-Preserving Surgery； Low Anterior Resection Syndrome； Rectal Cancer
摘要: 随着现代医疗技术的不断发展，直肠癌患者更加倾向于选择保肛手术。低位前切除综合征(Low Anterior Resection Syndrome, LARS)作为保肛术后常见的排便功能障碍问题，对众多直肠癌患者术后的生活质量产生了深远影响。如何客观评估LARS的风险因素，正确认识其生理病理机制，从而采取科学的防治措施已成为临床上亟待解决的问题。本综述系统概括了LARS的定义、评价方法、病理生理机制以及防治措施，结合当前最新的研究进展，为临床医生优化治疗方案、改善直肠癌患者预后提供了理论基础。
Abstract: With the continuous advancement of modern medical technology, patients with rectal cancer are more inclined to choose sphincter-preserving surgery. Low anterior resection syndrome (LARS), a common defecation dysfunction problem after sphincter-preserving surgery, has a profound impact on the postoperative quality of life of many rectal cancer patients. How to objectively evaluate the risk factors of LARS, correctly understand its physiological and pathological mechanisms, and thus adopt scientific prevention and treatment measures has become an urgent clinical issue. This review summarizes the definition, evaluation methods, pathophysiological mechanisms, and prevention and treatment measures of LARS. Combining the latest research progress, it provides a theoretical basis for clinicians to optimize treatment plans and improve the prognosis of rectal cancer patients.
文章引用：黄晓嵩, 吴雪松. 直肠前切除综合征的研究进展[J]. 临床医学进展, 2026, 16(2): 2568-2575. https://doi.org/10.12677/acm.2026.162664

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