针灸联合维生素B12治疗自身免疫性胃炎一例
A Medical Case of Acupuncture Combined with Vitamin B12 in the Management of Autoimmune Gastritis
DOI: 10.12677/tcm.2026.152120, PDF,    科研立项经费支持
作者: 丁亚文, 吴璐一, 刘慧荣, 李国娜*, 吴焕淦*：上海中医药大学附属岳阳中西医结合医院，上海；上海市针灸经络研究所，上海；杨 答：河南中医药大学针灸推拿学院，河南 郑州；林亚莹, 胡文清, 孙 吉, 李 璟：上海中医药大学附属岳阳中西医结合医院，上海
关键词: 自身免疫性胃炎；艾灸；针刺；维生素B12；病案；Autoimmune Gastritis； Acupuncture； Moxibustion； Vitamin B12； Medical Case
摘要: 自身免疫性胃炎(Autoimmune gastritis, AIG)是一种由自身免疫机制介导的慢性胃黏膜炎症性疾病，早期常缺乏特异性胃肠道症状，但可伴随焦虑、抑郁等负性情绪，显著影响患者生活质量。本文报道一例女性AIG患者合并负性情绪的综合治疗过程。该患者在接受针灸联合维生素B12干预后，不仅食欲减退、早饱感等非特异性消化道症状显著缓解，焦虑抑郁情绪亦明显改善，胃镜及病理评估显示胃黏膜萎缩程度有所减轻。整个治疗过程中未出现明显不良反应。本病例提示，针灸联合维生素B12可能为AIG患者，尤其是伴有情绪障碍者，提供一种安全、有效的辅助治疗策略。
Abstract: Autoimmune gastritis (AIG) is a chronic inflammatory disorder of the gastric mucosa mediated by autoimmune mechanisms. In its early stages, AIG often presents with nonspecific or minimal gastrointestinal symptoms; however, it may be accompanied by negative affective states such as anxiety and depression, which can significantly impair patients’ quality of life. We report a case of a female patient with AIG and comorbid psychological distress who underwent integrative treatment combining acupuncture and vitamin B12 supplementation. Following the intervention, the patient experienced marked improvement in nonspecific gastrointestinal symptoms—including loss of appetite and early satiety—as well as notable alleviation of anxiety and depressive symptoms. Endoscopic and histopathological evaluations further revealed a reduction in the severity of gastric mucosal atrophy. No significant adverse effects were observed throughout the treatment course. This case suggests that the combination of acupuncture and vitamin B12 may represent a safe and effective adjunctive therapeutic approach for patients with AIG, particularly those with concomitant mood disturbances.
文章引用：丁亚文, 杨答, 林亚莹, 吴璐一, 刘慧荣, 胡文清, 孙吉, 李璟, 李国娜, 吴焕淦. 针灸联合维生素B12治疗自身免疫性胃炎一例[J]. 中医学, 2026, 15(2): 375-382. https://doi.org/10.12677/tcm.2026.152120

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