从“痰、瘀”论治慢性冠脉综合征的进展研究

Research Progress on the Treatment of Chronic Coronary Syndrome from the Perspective of Phlegm and Blood Stasis

摘要: 心血管疾病是人类死亡的主要原因，严重威胁着人类健康，慢性冠脉综合征是心血管疾病的一类重要类型，根据其临床表现多归属为中医“胸痹心痛”范畴，而随着中医学的发展，“痰瘀互结”逐渐被认为是胸痹心痛的核心病机。本文系统梳理痰瘀互结理论在胸痹心痛中的病机演变，并探讨其与现代医学脂质代谢紊乱、炎症反应机制密切相关，同时总结出化痰祛瘀法在经方、自拟方及中成药中的应用进展，以期为从“痰瘀”论治慢性冠脉综合征的提供理论依据及临床参考。

Abstract: Cardiovascular diseases are the leading cause of human death and pose a serious threat to human health. Chronic coronary syndrome is an important type of cardiovascular disease, which is mostly classified under the category of “chest pain and heart pain” in traditional Chinese medicine (TCM) based on its clinical manifestations. With the development of TCM, “phlegm and blood stasis interconnection” has gradually been recognized as the core pathogenesis of chest pain and heart pain. This article systematically reviews the evolution of the pathogenesis of phlegm and blood stasis interconnection in chest pain and heart pain, and explores its close relationship with modern medical lipid metabolism disorders and inflammatory response mechanisms. At the same time, it summarizes the application progress of the phlegm-resolving and blood stasis-removing method in classical prescriptions, self-prescribed formulas, and Chinese patent medicines, with the aim of providing theoretical basis and clinical reference for the treatment of chronic coronary syndrome from the perspective of “phlegm and blood stasis”.