雌激素对慢性肾脏病发生发展影响
The Effects of Estrogen on the Occurrence and Development of Chronic Kidney Disease
DOI: 10.12677/acm.2026.163767, PDF,    科研立项经费支持
作者: 赵欣蕾, 杨 敏*, 徐毓轲：昆明医科大学第二附属医院肾脏内科，云南 昆明
关键词: 雌激素；慢性肾脏病；作用机制；Estrogen； Chronic Kidney Disease； Mechanism of Action
摘要: 慢性肾脏病(CKD)已成为全球范围内的重大公共卫生问题，其流行病学存在已知的性别差异，研究表明肾脏疾病中的性别二态性与雌激素的作用密切相关，但目前潜在的作用机制尚不明确。本文主要对雌激素对肾脏保护作用的可能机制进行阐述，为临床延缓CKD进展提供新的理论基础，从而在未来提供新的治疗靶点。
Abstract: Chronic kidney disease (CKD) has become a major public health problem worldwide, with known epidemiological and outcome differences between the sexes. It has been shown that sex dimorphism in kidney disease is closely related to the action of estrogen, but the underlying mechanisms are still unclear. This paper mainly expounds on the possible mechanisms of estrogen on renal protection, in order to provide a new theoretical basis for the clinical delay of CKD progression, thereby providing new treatment targets in the future.
文章引用：赵欣蕾, 杨敏, 徐毓轲. 雌激素对慢性肾脏病发生发展影响[J]. 临床医学进展, 2026, 16(3): 99-104. https://doi.org/10.12677/acm.2026.163767

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