和胃固妊汤联合穴位外敷改善肝胃不和型妊娠剧吐的临床研究

Clinical Study on the Combined Use of Hewei Guren Decotion Combined with External Application of Hewei Antai Ointment Applied Externally to Shenque Acupoint to Improve Hepatic Gastric Disharmony Type of Preeclampsia

摘要: 目的：探讨和胃固妊汤联合穴位外敷改善肝胃不和型妊娠剧吐的临床效果。方法：选择2022年1月~2025年12月在医院就诊的孕妇230例，根据不同用药方案分为联合组和对照组(各115例)。在常规治疗基础上，两组均使用和胃安胎膏外敷神阙穴，联合组加用和胃固妊汤。治疗后对两组临床疗效、治疗前后尿酮体及中医证候积分变化情况进行统计分析。结果：联合组总有效率明显高于对照组(P < 0.05)。两组治疗3 d后、治疗10 d后的尿酮体水平、中医证候积分较治疗前均明显下降，联合组在治疗后两个时间点的尿酮体水平、中医证候积分均低于对照组(P < 0.05)。结论：进行常规治疗的基础上使用和胃安胎膏外敷神阙穴，同时加用和胃固妊汤能够显著缓解肝胃不和型妊娠剧吐。

Abstract: Objective: To explore the clinical effect of Hewei gupitang combined with Acupoint External Application on hyperemesis gravidarum of liver stomach disharmony type. Method: A total of 230 pregnant women in the hospital from January 2022 to December 2025 were selected and divided into the combination group and the control group (115 cases in each group) according to different medication regimens. On the basis of conventional treatment, both groups were treated with Hewei Antai ointment for external application at Shenque point, and the combined group was additionally treated with Hewei Gupi decoction. After treatment, the clinical efficacy, the changes of urine ketone body and TCM syndrome score before and after treatment in the two groups were statistically analyzed. Result: The total effective rate of the combined group was higher (P < 0.05). After 3 days and 10 days of treatment, the levels of urinary ketones and TCM syndrome scores in both groups decreased significantly compared to before treatment. Among them, the combined group had significantly lower levels of urinary ketones and TCM syndrome scores at both time points after treatment compared to the control group (P < 0.05). Conclusion: On the basis of routine treatment, applying Hewei Antai ointment externally to Shenque acupoint, and adding Hewei Guyuai decoction can significantly alleviate liver stomach disharmony type of severe vomiting during pregnancy.