以反复贫血及腹痛为首发症状的一例Castleman病诊疗经过及文献复习

Diagnosis and Treatment Process of a Case of Castleman Disease with Recurrent Anemia and Abdominal Pain as the Initial Symptoms, along with a Literature Review

摘要: 目的：探讨儿童Castleman病(CD)的临床特点，提高对该病诊断、治疗及预后的了解。方法：回顾性分析青岛大学附属医院收治的1例儿童CD患者临床及病理资料。同时检索中国知网、万方医学网、Pubmed中英文数据库对相关文献进行复习。结果：本例患儿以反复贫血及腹痛为首发症状，增强CT提示腹腔均匀强化软组织肿块影，行腹腔镜下切除手术。术后随访半年无复发。结论：儿童Castleman病较为罕见，其诊断需要结合临床、影像及病理综合判断，提高对该病的认识，有助于减少漏诊、误诊。

Abstract: Objective: To explore the clinical characteristics of Castleman disease (CD) in children and enhance understanding of its diagnosis, treatment, and prognosis. Methods: A retrospective analysis was conducted on the clinical and pathological data of a pediatric CD patient admitted to the Affiliated Hospital of Qingdao University. Additionally, relevant literature was reviewed by searching the Chinese and English databases of CNKI, Wanfang Medical Network, and PubMed. Results: This patient presented with recurrent anemia and abdominal pain as the initial symptoms. Enhanced CT scan revealed a uniformly enhanced soft tissue mass in the abdominal cavity, and laparoscopic resection was performed. Follow-up for half a year after surgery showed no recurrence. Conclusion: Castleman disease in children is relatively rare, and its diagnosis requires a comprehensive assessment of clinical, imaging, and pathological findings. Improving awareness of this disease can help reduce missed and incorrect diagnoses.