导尿管相关性尿路感染的中西医研究进展

Research Progress of Catheter-Associated Urinary Tract Infections in Integrative Chinese and Western Medicine

摘要: 导尿管相关尿路感染(catheter-associated urinary tract infections, CAUTI)是临床最常见的医院获得性感染之一，主要由留置导尿管引发。其核心病理特征为细菌侵袭尿路黏膜导致炎症反应，这会延长患者住院时间、增加医疗成本及病死率，且抗生素耐药问题日益突出。中医将其归属于“淋证”范畴，在辨证论治与整体调理方面具有独特优势。本文从CAUTI的西医发病机制、诊疗与预防进展，中医病因病机、辨证治疗体系，以及中西医结合研究现状等方面进行综述，结合近年国内外文献，总结当前研究成果与不足，展望未来研究方向，为临床优化CAUTI防治方案提供参考。

Abstract: Catheter-associated urinary tract infections (CAUTI) rank among the most prevalent hospital-acquired infections in clinical settings, primarily stemming from indwelling urinary catheters. Their core pathological feature involves bacterial invasion of the urinary tract mucosa triggering inflammatory responses. This condition prolongs patient hospital stays, increases healthcare costs and mortality rates, while antibiotic resistance poses an increasingly critical challenge. Traditional Chinese Medicine (TCM) classifies CAUTI under the category of “lin zheng” offering unique advantages in syndrome differentiation and holistic regulation. This review examines Western medical perspectives on CAUTI pathogenesis, diagnosis, treatment, and prevention; TCM etiology, pathogenesis, and syndrome differentiation-based therapeutic systems; and current integrated TCM-Western medicine research. Drawing on recent domestic and international literature, it summarizes existing research achievements and gaps while outlining future research directions, aiming to provide references for optimizing clinical CAUTI prevention and treatment strategies.