应用OCTA评价糖尿病视网膜病变患者的 视网膜微循环与颈动脉狭窄的研究进展

Application of OCTA in the Evaluation of Retinal Microcirculation and Carotid Artery Stenosis in Diabetic Retinopathy

摘要: 糖尿病视网膜病变(Diabetic Retinopathy, DR)是糖尿病(Diabetes Mellitus, DM)的一种威胁视力的微血管并发症，是全球导致失明的主要原因。其发病机制与视网膜微循环障碍密切相关。颈动脉是供应大脑和眼部的主要血管，颈动脉病理改变进而影响视网膜血流。近年来研究表明，糖尿病视网膜病变与颈动脉狭窄(Carotid Artery Stenosis, CAS)之间存在密切关联。随着研究的深入，OCTA (Optical Coherence Tomography Angiography, OCTA)技术在评估糖尿病视网膜病变患者的视网膜微循环方面展现出巨大潜力，为探讨其与颈动脉狭窄的关系提供了新的视角。然而，目前仍需更多临床研究来验证OCTA在评估糖尿病视网膜病变与颈动脉狭窄关系中的应用价值，以及深入探讨其潜在的诊断和预测作用。期望可以更全面地了解DR患者的血管病变情况，为临床诊疗提供更精准的依据。

Abstract: Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus (DM) that threatens vision and is a leading cause of blindness worldwide. Its pathogenesis is closely associated with retinal microcirculatory disturbances. The carotid artery, the primary vessel supplying the brain and eye, exhibits pathological changes that subsequently affect retinal blood flow. Recent studies have demonstrated a significant correlation between diabetic retinopathy and carotid artery stenosis (CAS). With advancing research, OCTA (optical coherence tomography angiography) technology has shown great potential in evaluating retinal microcirculation in patients with diabetic retinopathy, providing a novel perspective for investigating its relationship with carotid artery stenosis. However, further clinical studies are still required to validate the application value of OCTA in assessing the relationship between diabetic retinopathy and carotid artery stenosis, as well as to explore its potential diagnostic and predictive roles. It is anticipated that a more comprehensive understanding of vascular pathology in DR patients will be achieved, offering more precise evidence for clinical diagnosis and treatment.