气温对血清尿酸浓度的影响及其机制研究进展
Research Progress on the Influence of Temperature on Serum Uric Acid Concentration and Its Mechanisms
摘要: 本研究旨在综述气温对血清尿酸浓度影响及其机制的研究进展，为临床实践和公共卫生政策制定提供参考。过往研究表明，气温与血清尿酸浓度存在一定关系，不同地区、人群的研究结果虽有所差异，但总体提示气温变化可能影响血清尿酸水平。在影响机制方面，气温可能通过体温调节影响尿酸代谢酶活性，以及通过血液循环影响尿酸运输，同时内分泌系统的激素分泌变化和神经内分泌调节也在其中发挥作用。然而，当前研究存在结果不一致、机制研究局限性等问题。未来研究应关注多中心大样本研究、深入探究复杂机制，并借助新技术如基因检测和大数据分析，以更好地理解气温与血清尿酸浓度的关系及其机制，为相关疾病的预防和治疗提供更精准的策略。
Abstract: This study aims to review the research progress on the effect of temperature on serum uric acid concentration and its mechanism, providing reference for clinical practice and public health policy-making. Previous studies have shown that there is a certain relationship between temperature and serum uric acid concentration. Although the research results in different regions and populations are different, they generally suggest that temperature changes may affect serum uric acid levels. In terms of the mechanism of influence, temperature may affect the activity of uric acid metabolic enzymes through thermoregulation, and affect uric acid transport through blood circulation. At the same time, changes in hormone secretion in the endocrine system and neuroendocrine regulation also play a role in it. However, there are problems such as inconsistent results and limitations in mechanism research in the current research. Future research should focus on multi-center large-sample studies, deeply explore complex mechanisms, and use new technologies such as gene detection and big data analysis to better understand the relationship between temperature and serum uric acid concentration and its mechanisms, providing more precise strategies for the prevention and treatment of related diseases.
文章引用：陈明轩, 宋媛. 气温对血清尿酸浓度的影响及其机制研究进展[J]. 临床医学进展, 2026, 16(3): 3291-3297. https://doi.org/10.12677/acm.2026.1631135

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