三合清中汤联合耳穴压豆治疗胃疡病(湿热证)的临床疗效观察与分析

Clinical Observation and Analysis of the Combined Use of Sanheqingzhong Decoction and Auricular Acupuncture with Seed Pressure in the Treatment of Gastric Ulcer (Damp-Heat Pattern)

摘要: 目的：探讨三合清中汤联合耳穴压豆对胃疡病(湿热证)患者的临床疗效及安全性。方法：采用随机对照试验设计，纳入2025年1月至2025年12月张家界市中医医院收治的100例胃疡病(湿热证)患者，随机分为实验组和对照组各50例。对照组给予雷贝拉唑钠肠溶胶囊治疗；实验组在对照组治疗基础上联合三合清中汤内服及耳穴压豆治疗，治疗周期均为7天。评估两组治疗前后中医证候积分变化、胃镜下溃疡愈合情况及不良反应发生率。结果：治疗后，实验组中医证候总有效率显著高于对照组，差异具有统计学意义(P < 0.05)；实验组胃镜下溃疡愈合总有效率亦显著高于对照组(P < 0.05)。实验组治疗后中医证候积分显著低于对照组(P < 0.001)。两组不良事件发生率分别为6.0%和4.0%，差异无统计学意义(P > 0.05)。结论：三合清中汤联合耳穴压豆可显著改善胃疡病(湿热证)患者的临床症状，促进溃疡愈合，且不增加不良反应发生风险，具有较高的临床应用价值。

Abstract: Objective: To investigate the clinical efficacy and safety of Sanheqingzhong Decoction combined with auricular seed pressing in patients with gastric ulcer (damp-heat pattern). Methods: A randomized controlled trial design was adopted. One hundred patients with gastric ulcer (damp-heat pattern) admitted to Zhangjiajie Traditional Chinese Medicine Hospital from January 2025 to December 2025 were enrolled and randomly divided into an experimental group and a control group, with 50 patients in each group. The control group received treatment with enteric-coated rabeprazole sodium capsules. The experimental group received the same treatment as the control group plus oral administration of Sanheqingzhong Decoction and auricular acupressure therapy. The treatment period for both groups was 7 days. Changes in Traditional Chinese Medicine (TCM) syndrome scores before and after treatment, endoscopic ulcer healing rates, and adverse reaction incidence rates were evaluated in both groups. Results: After treatment, the total effective rate of TCM syndromes in the experimental group was significantly higher than that in the control group (P < 0.05). The total effective rate of endoscopic ulcer healing in the experimental group was also significantly higher than that in the control group (P < 0.05). The TCM syndrome scores in the experimental group were significantly lower than those in the control group (P < 0.001). The incidence rates of adverse events in the two groups were 6.0% and 4.0%, respectively, with no statistically significant difference (P > 0.05). Conclusion: The combination of Sanheqingzhong Decoction and auricular seed therapy significantly improves clinical symptoms and promotes ulcer healing in patients with gastric ulcer (damp-heat pattern) without increasing the risk of adverse reactions, demonstrating high clinical application value.