脑卒中居家康复效果的Meta分析
Meta-Analysis of the Effects of Home-Based Rehabilitation for Stroke
DOI: 10.12677/ns.2026.153084, PDF,    科研立项经费支持
作者: 吕梅芬, 刘华丽, 叶 芳, 杨丽娜, 李石秀, 杨 敏, 温荣爱, 孟李叶, 杨永花, 颜 娜*:云南省曲靖中心医院康复医学科,云南 曲靖
关键词: 脑卒中居家康复Meta分析运动功能生活质量Stroke Home-Based Rehabilitation Meta-Analysis Motor Function Quality of Life
摘要: 目的:系统评价脑卒中患者居家康复对运动功能、日常生活活动能力及生活质量的影响。方法:检索中国知网、万方、PubMed、Cochrane Library等数据库中建库至2024年12月的随机对照试验(RCT),采用RevMan5.3和Stata17.0进行Meta分析。结果:共纳入28篇RCT (总样本量3,520例)。Meta分析显示,居家康复能显著改善患者运动功能(SMD = 0.82, 95% CI: 0.65~1.02)、日常生活活动能力(ADL) (SMD = 0.76, 95% CI: 0.58~0.94)及生活质量(SMD = 0.71, 95% CI: 0.53~0.89)。亚组分析表明,干预周期 ≥ 12周、结合远程技术的康复方案效果更优。结论:居家康复是脑卒中患者有效的康复模式,建议结合个体化方案与远程监测技术推广应用。
Abstract: Objective: To systematically evaluate the effects of home-based rehabilitation on motor function, activities of daily living (ADL), and quality of life in stroke patients. Methods: Randomized controlled trials (RCTs) published from the inception of databases to December 2024 were searched in databases including CNKI, Wanfang, PubMed, and Cochrane Library. Meta-analysis was conducted using RevMan 5.3 and Stata 17.0. Results: A total of 28 RCTs (with a total sample size of 3,520 participants) were included. The meta-analysis showed that home-based rehabilitation significantly improved motor function (SMD = 0.82, 95% CI: 0.65-1.02), activities of daily living (ADL) (SMD = 0.76, 95% CI: 0.58-0.94), and quality of life (SMD = 0.71, 95% CI: 0.53-0.89). Subgroup analysis indicated that rehabilitation programs with an intervention duration of ≥ 12 weeks and those incorporating remote technology were more effective. Conclusion: Home-based rehabilitation is an effective rehabilitation model for stroke patients. It is recommended to promote its application with individualized programs and remote monitoring technology.
文章引用:吕梅芬, 刘华丽, 叶芳, 杨丽娜, 李石秀, 杨敏, 温荣爱, 孟李叶, 杨永花, 颜娜. 脑卒中居家康复效果的Meta分析[J]. 护理学, 2026, 15(3): 186-197. https://doi.org/10.12677/ns.2026.153084

参考文献

[1] 王陇德. 中国脑卒中防治报告[M]. 北京: 人民卫生出版社, 2021.
[2] Zhou, M., Wang, H., Zhu, J., Chen, W., Wang, L., Liu, S., et al. (2016) Cause-Specific Mortality for 240 Causes in China during 1990-2013: A Systematic Subnational Analysis for the Global Burden of Disease Study 2013. The Lancet, 387, 251-272. [Google Scholar] [CrossRef] [PubMed]
[3] Langhorne, P. and Baylan, S. (2017) Early Supported Discharge Services for People with Acute Stroke. Cochrane Database of Systematic Reviews, 2017, CD000443. [Google Scholar] [CrossRef] [PubMed]
[4] 张通. 中国脑卒中康复治疗指南[J]. 中华物理医学与康复杂志, 2019, 41(4): 241-250.
[5] Higgins, J.P. and Green, S. (2011) Cochrane Handbook for Systematic Reviews of Interventions. Wiley.
[6] 刘鸣. 循证医学[M]. 北京: 人民卫生出版社, 2018.
[7] Sacco, R.L., Kasner, S.E., Broderick, J.P., Caplan, L.R., Connors, J.J., Culebras, A., et al. (2013) An Updated Definition of Stroke for the 21st Century. Stroke, 44, 2064-2089. [Google Scholar] [CrossRef] [PubMed]
[8] Winstein, C.J., Stein, J., Arena, R., Bates, B., Cherney, L.R., Cramer, S.C., et al. (2016) Guidelines for Adult Stroke Rehabilitation and Recovery. Stroke, 47, e98-e169. [Google Scholar] [CrossRef] [PubMed]
[9] Quinn, T.J., Langhorne, P. and Stott, D.J. (2011) Barthel Index for Stroke Trials: Development, Properties, and Application. Stroke, 42, 1146-1151. [Google Scholar] [CrossRef] [PubMed]
[10] Moher, D., Liberati, A., Tetzlaff, J. and Altman, D.G. (2009) Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLOS Medicine, 6, e1000097. [Google Scholar] [CrossRef] [PubMed]
[11] Kwakkel, G., van Peppen, R., Wagenaar, R.C., Wood Dauphinee, S., Richards, C., Ashburn, A., et al. (2004) Effects of Augmented Exercise Therapy Time after Stroke: A Meta-Analysis. Stroke, 35, 2529-2539. [Google Scholar] [CrossRef] [PubMed]
[12] 贾子善. 脑卒中康复治疗技术[M]. 北京: 人民军医出版社, 2020.
[13] Legg, L.A., Lewis, S.R., Schofield-Robinson, O.J., Drummond, A. and Langhorne, P. (2017) Occupational Therapy for Adults with Problems in Activities of Daily Living after Stroke. Cochrane Database of Systematic Reviews, 2023, CD003585. [Google Scholar] [CrossRef] [PubMed]
[14] 倪朝民. 神经康复学[M]. 北京: 人民卫生出版社, 2019.
[15] Carod-Artal, F.J. and Egido, J.A. (2009) Quality of Life after Stroke: The Importance of a Good Recovery. Cerebrovascular Diseases, 27, 204-214. [Google Scholar] [CrossRef] [PubMed]
[16] 李玲. 脑卒中患者生活质量研究进展[J]. 中国康复医学杂志, 2020, 35(3): 358-361.
[17] Billinger, S.A., Arena, R., Bernhardt, J., Eng, J.J., Franklin, B.A., Johnson, C.M., et al. (2014) Physical Activity and Exercise Recommendations for Stroke Survivors. Stroke, 45, 2532-2553. [Google Scholar] [CrossRef] [PubMed]
[18] Chen, J., Sun, D., Zhang, S., Shi, Y., Qiao, F., Zhou, Y., et al. (2020) Effects of Home-Based Telerehabilitation in Patients with Stroke: A Randomized Controlled Trial. Neurology, 95, e2313-e2323. [Google Scholar] [CrossRef] [PubMed]
[19] Veerbeek, J.M., van Wegen, E., van Peppen, R., et al. (2014) What Is the Evidence for Physical Therapy after Stroke? Acta Neurologica Scandinavica, 129, 243-251.
[20] Sterne, J.A.C., Sutton, A.J., Ioannidis, J.P.A., Terrin, N., Jones, D.R., Lau, J., et al. (2011) Recommendations for Examining and Interpreting Funnel Plot Asymmetry in Meta-Analyses of Randomised Controlled Trials. British Medical Journal, 343, d4002. [Google Scholar] [CrossRef] [PubMed]
[21] 王茂斌. 脑卒中的康复医疗[M]. 北京: 中国科学技术出版社, 2018.
[22] Laver, K.E., Adey-Wakeling, Z., Crotty, M., Lannin, N.A., George, S. and Sherrington, C. (2020) Telerehabilitation Services for Stroke. Cochrane Database of Systematic Reviews, 2020, CD010255. [Google Scholar] [CrossRef] [PubMed]
[23] 陈立典. 中国传统康复技能[M]. 北京: 人民卫生出版社, 2019.
[24] Kleim, J.A. and Jones, T.A. (2008) Principles of Experience-Dependent Neural Plasticity: Implications for Rehabilitation after Brain Damage. Journal of Speech, Language, and Hearing Research, 51, S225-S229. [Google Scholar] [CrossRef] [PubMed]
[25] Loh, S.Y. and Lee, S.Y. (2020) Effects of Home-Based Cardiac Rehabilitation in Patients with Coronary Artery Disease: A Meta-Analysis. Heart Lung, 49, 894-901.
[26] Cramer, S.C., Sur, M., Dobkin, B.H., et al. (2011) Harnessing Neuroplasticity for Clinical Applications. Brain, 134, 1591-1609.
[27] 胡永善. 社区康复学[M]. 北京: 人民卫生出版社, 2018.
[28] Egger, M., Smith, G.D., Schneider, M. and Minder, C. (1997) Bias in Meta-Analysis Detected by a Simple, Graphical Test. British Medical Journal, 315, 629-634. [Google Scholar] [CrossRef] [PubMed]
[29] Feigin, V.L., Stark, B.A., Johnson, C.O., Roth, G.A., Bisignano, C., Abady, G.G., et al. (2021) Global, Regional, and National Burden of Stroke and Its Risk Factors, 1990-2019: A Systematic Analysis for the Global Burden of Disease Study 2019. The Lancet Neurology, 20, 795-820. [Google Scholar] [CrossRef] [PubMed]
[30] Anderson, C., Rubenach, S., Mhurchu, C.N., Clark, M., Spencer, C. and Winsor, A. (2000) Home or Hospital for Stroke Rehabilitation? Results of a Randomized Controlled Trial. Stroke, 31, 1024-1031. [Google Scholar] [CrossRef] [PubMed]
[31] Higgins, J.P.T., Thompson, S.G., Deeks, J.J. and Altman, D.G. (2003) Measuring Inconsistency in Meta-Analyses. British Medical Journal, 327, 557-560. [Google Scholar] [CrossRef] [PubMed]
[32] 吴毅. 脑卒中康复评估与治疗[M]. 上海: 上海科学技术出版社, 2020.
[33] Duncan, P.W., Zorowitz, R., Bates, B., Choi, J.Y., Glasberg, J.J., Graham, G.D., et al. (2005) Management of Adult Stroke Rehabilitation Care: A Clinical Practice Guideline. Stroke, 36, e100-e143. [Google Scholar] [CrossRef] [PubMed]
[34] 徐婕, 王清, 邵佳宁, 等. 脑卒中患者居家康复运动自我决策困境的质性研究[J]. 护理学杂志, 2025, 40(21): 84-88.
[35] Chen, Y., Abel, K.T., Janecek, J.T., Chen, Y., Zheng, K. and Cramer, S.C. (2019) Home-Based Technologies for Stroke Rehabilitation: A Systematic Review. International Journal of Medical Informatics, 123, 11-22. [Google Scholar] [CrossRef] [PubMed]
[36] Lin, Z., Zhang, X., Jiang, Y., et al. (2023) Effectiveness of a Home-Based Telerehabilitation Program for Post-Stroke Patients: A Randomized Controlled Trial. Clinical Rehabilitation, 37, 621-630.
[37] 陈伟, 王静, 刘洋. 家庭康复联合智能设备对脑卒中患者上肢功能的影响[J]. 中国康复医学杂志, 2022, 37(8): 1025-1029.
[38] Lin, Y., Wang, J., Zhang, H., et al. (2024) Long-Term Effects of a Structured Home-Based Exercise Program on Motor Recovery and Quality of Life in Stroke Survivors: A Randomized Controlled Trial. Disability and Rehabilitation, 46, 155-163.
[39] 张明, 李红, 赵磊. 基于远程指导的居家康复对脑卒中患者步行能力及日常生活活动能力的影响[J]. 中华物理医学与康复杂志, 2023, 45(4): 289-293.
[40] Gebrye, T., Mbada, C., Fatoye, F., & Anazodo, C. (2024) Effectiveness of Telerehabilitation on Quality of Life in Stroke Survivors: A Systematic Review and Meta-Analysis. Physical Therapy Reviews, 29, 187-196. [Google Scholar] [CrossRef