超声定量技术在代谢相关脂肪性肝病肝脂肪 含量评估中的研究进展
Advances in Ultrasound-Based Quantitative Techniques for Assessing Hepatic Steatosis in Metabolic-Associated Fatty Liver Disease
摘要: 代谢相关脂肪性肝病(MAFLD)已然成为当前全球最常见的慢性肝病，其疾病谱涵盖单纯脂肪变性、脂肪性肝炎、肝纤维化及肝硬化。早期、无创、精准评估肝脏脂肪变性程度，对于MAFLD的筛查诊断、风险分层、疗效监测及长期随访管理具有重要意义。传统超声依赖主观判断，重复性差；肝活检为有创金标准，难以普及。近年来，随着超声定量技术的快速发展，为肝脂肪含量的无创、客观评估提供了新手段。本文旨在对目前超声定量技术在MAFLD肝脏脂肪含量评估中的研究进展进行综述。
Abstract: Metabolic-associated fatty liver disease (MAFLD) is currently the leading cause of chronic liver disease worldwide, encompassing simple steatosis, steatohepatitis, fibrosis, and cirrhosis. Early, non-invasive, and accurate evaluation of hepatic steatosis is crucial for screening, risk stratification, and longitudinal management of MAFLD. While traditional ultrasound is limited by subjectivity and poor reproducibility, and liver biopsy is constrained by its invasive nature, recent developments in quantitative ultrasound (QUS) technology have introduced objective and non-invasive alternatives. This review summarizes the recent research advances in the application of quantitative ultrasound for assessing hepatic fat content in MAFLD.
文章引用：李灵凌, 张群霞. 超声定量技术在代谢相关脂肪性肝病肝脂肪 含量评估中的研究进展[J]. 临床医学进展, 2026, 16(3): 3632-3638. https://doi.org/10.12677/acm.2026.1631171

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