右美托咪定对七氟烷麻醉老年骨折手术患者的应用效果

The Application Effect of Dexmedetomidine on Elderly Fracture Surgery Patients Anesthetized with Sevoflurane

摘要: 目的：研究右美托咪定应用于老年骨折七氟烷麻醉手术患者中的作用。方法：纳入本院接收的老年骨折手术患者(时间为2024年11月至2025年12月) 64例，以麻醉方式不同为依据，分为对照组(七氟烷麻醉，32例)与试验组(七氟烷联合右美托咪定麻醉，32例)。对比两组血流动力学指标、认知功能和不良反应。结果：气管插管、麻醉维持即刻、切皮及术毕时，试验组心率与平均动脉压较对照组波动幅度均更小(P < 0.05)；术后不同时间段，试验组认知功能评分高于术前及对照组(P < 0.05)；试验组不良反应少于对照组(P < 0.05)。结论：老年骨折手术患者采用七氟烷结合右美托咪定麻醉，能确保血流动力学更平稳，还能减轻对认知功能的影响，且安全性佳。

Abstract: Objective: To investigate the effects of dexmedetomidine in elderly patients undergoing fracture surgery under sevoflurane anesthesia. Methods: A total of 64 elderly fracture patients admitted to our hospital (from November 2024 to December 2025) were included and divided into a control group (sevoflurane anesthesia, 32 cases) and an experimental group (sevoflurane combined with dexmedetomidine anesthesia, 32 cases) based on the anesthesia method. The hemodynamic parameters, cognitive function, and adverse reactions were compared between the two groups. Results: At the time of intubation, during anesthesia maintenance, at skin incision, and at the end of surgery, the experimental group exhibited smaller fluctuations in heart rate and mean arterial pressure compared to the control group (P < 0.05). In the postoperative period, the cognitive function scores of the experimental group were higher than those of the preoperative period and the control group (P < 0.05). The experimental group had fewer adverse reactions than the control group (P < 0.05). Conclusion: Using sevoflurane combined with dexmedetomidine anesthesia in elderly fracture patients ensures more stable hemodynamics, reduces the impact on cognitive function, and demonstrates good safety.