五苓散加味治疗椎管内麻醉混合痔术后尿潴留的临床效果
Clinical Effect of Modified Wuling San on Postoperative Urinary Retention in Patients Undergoing Mixed Hemorrhoid Surgery under Spinal Anesthesia
DOI: 10.12677/jcpm.2026.52099, PDF,    科研立项经费支持
作者: 李成良*, 李星宇, 李知秋:扬州大学医学部,江苏 扬州;李晟玮#:扬州大学医学部,江苏 扬州;扬州市中医院肛肠科,江苏 扬州
关键词: 混合痔椎管内麻醉尿潴留五苓散加味中医药术后并发症Mixed Hemorrhoids Spinal Anesthesia Urinary Retention Wuling San Traditional Chinese Medicine Postoperative Complications
摘要: 目的:探讨五苓散加味在椎管内麻醉下混合痔术后尿潴留的治疗效果,为术后尿潴留患者提供安全、有效的中医药干预方案。方法:选取肛肠外科行椎管内麻醉混合痔手术的60例患者,随机分为观察组和对照组,各30例。对照组给予常规围手术期护理 + 甲硫酸新斯的明肌注,观察组给予常规围手术期护理 + 口服五苓散加味。比较两组术后首次自主排尿时间、首次排尿量、膀胱残余尿量、腹部症状评分、排尿状况评分、疼痛评分及临床总有效率。结果:观察组首次排尿时间明显早于对照组(14.45 ± 5.31 h vs. 17.24 ± 5.23 h, P < 0.05);首次排尿量增加(463.45 ± 100.36 mL vs. 380.07 ± 100.46 mL, P < 0.01);膀胱残余尿量明显减少(81.70 ± 41.59 mL vs. 108.79 ± 28.56 mL, P < 0.01)。术后24 h及3 d疼痛评分低于对照组(P < 0.01)。腹部症状、排尿状况及排尿持续时间评分改善显著,临床总有效率达93.33%,明显高于对照组的73.33% (P < 0.05)。结论:五苓散加味能够有效缩短椎管内麻醉混合痔术后首次排尿时间、增加排尿量、减少膀胱残余尿量,同时改善腹部不适及排尿费力感,缓解术后疼痛,提高患者排尿舒适度和临床疗效。
Abstract: Objective: To investigate the therapeutic effect of modified Wuling San on postoperative urinary retention (PUR) in patients undergoing mixed hemorrhoid surgery under spinal anesthesia, and to provide a safe and effective traditional Chinese medicine (TCM) intervention for PUR. Methods: Sixty patients undergoing mixed hemorrhoid surgery under spinal anesthesia in the colorectal surgery department were randomly assigned to an observation group and a control group, 30 cases in each. The control group received conventional perioperative care with Intramuscular injection of neostigmine hydrochloride, while the observation group received oral administration of modified Wuling San in addition to routine care. Postoperative first spontaneous urination time, first voided volume, residual urine volume, abdominal symptoms score, urination status score, pain score, and overall clinical efficacy were compared between the two groups. Results: The observation group had significantly earlier first spontaneous urination time than the control group (14.45 ± 5.31 h vs. 17.24 ± 5.23 h, P < 0.05), greater first voided volume (463.45 ± 100.36 mL vs. 380.07 ± 100.46 mL, P < 0.01), and lower residual urine volume (81.70 ± 41.59 mL vs. 108.79 ± 28.56 mL, P < 0.01). Pain scores at 24 h and 3 d postoperatively were significantly lower in the observation group (P < 0.01). Abdominal symptom scores, urination status scores, and urination duration scores improved significantly, and the overall clinical efficacy rate was 93.33%, higher than that of the control group (73.33%, P < 0.05). Conclusion: Modified Wuling San effectively shortens the first urination time, increases voided volume, reduces residual urine, alleviates abdominal discomfort and difficulty in urination, and relieves postoperative pain in patients undergoing mixed hemorrhoid surgery under spinal anesthesia. This TCM intervention improves urination comfort and overall clinical efficacy.
文章引用:李成良, 李星宇, 李知秋, 李晟玮. 五苓散加味治疗椎管内麻醉混合痔术后尿潴留的临床效果[J]. 临床个性化医学, 2026, 5(2): 46-53. https://doi.org/10.12677/jcpm.2026.52099

参考文献

[1] Chen, Y., Cheng, Y., Wang, Q., Ye, B., Huang, C., Zhou, C., et al. (2021) Modified Procedure for Prolapse and Hemorrhoids: Lower Recurrence, Higher Satisfaction. World Journal of Clinical Cases, 9, 36-46. [Google Scholar] [CrossRef] [PubMed]
[2] 郭呈华, 车晓玉, 林芝, 等. 中国某健康体检人群痔的流行病学特征[J]. 北京大学学报(医学版), 2024, 56(5): 815-819.
[3] 史振滏, 陈苗苗, 赵艳艳, 等. 大黄浓缩抑菌液治疗混合痔临床观察[J]. 实用中医药杂志, 2025, 41(10): 2056-2058.
[4] 中国中西医结合学会大肠肛门病专业委员会. 中国痔病诊疗指南(2020) [J]. 结直肠肛门外科, 2020, 26(5): 519-533.
[5] 王娜, 汪彦良, 廖永新, 等. 低浓度布比卡因联合耳穴压豆对老年混合痔术后尿潴留及尿动力学指标的影响[J]. 中国老年学杂志, 2025, 45(3): 591-594.
[6] 张玲, 郭春光, 罗伟, 等. 五苓散联合核心控制训练及盆底肌电生物反馈治疗儿童脊髓损伤后神经源性膀胱尿潴留的疗效观察[J]. 世界中西医结合杂志, 2025, 20(9): 1814-1818.
[7] 闫军. 加味五苓散治疗产后尿潴留临床观察[J]. 中国中医药现代远程教育, 2023, 21(4): 100-102.
[8] 张渊博, 李京向, 段佳佳, 等. 隔五苓散药饼艾灸治疗硬膜外阻滞麻醉后急性尿潴留疗效观察[J]. 北京中医药, 2023, 42(7): 724-727.
[9] Sun, X., Xu, J., Zhu, C., Li, S., Jin, L. and Zhu, Z. (2024) Analysis of Factors Impacting Postoperative Pain and Quality of Life in Patients with Mixed Hemorrhoids: A Retrospective Study. World Journal of Gastrointestinal Surgery, 16, 731-739. [Google Scholar] [CrossRef] [PubMed]
[10] 严智敏, 赵晶. Kegel运动结合肛门安洗剂熏洗坐浴治疗对混合痔患者术后恢复的疗效观察[J]. 淮阴工学院学报, 2025, 34(5): 51-55.
[11] 智从从, 李雪, 程一乘, 等. 痔中西医结合诊疗指南(2025版)[J]. 中国全科医学, 2025, 28(26): 3217-3228.
[12] Narayanaswamy, C.Y.V., Sreevathsa, M.R., Chowdari, G.A. and Rao, K. (2022) Association of Muscle Fibers with Histopathology in Doughnut Specimens Following Stapled Hemorrhoidopexy and Their Impacts on Postoperative Outcomes. The Surgery Journal, 8, e199-e207. [Google Scholar] [CrossRef] [PubMed]
[13] Dong, W., An, B., Wang, Y., et al. (2021) Effect of Multimodal Analgesia on Gynecological Cancer Patients after Radical Resection. American Journal of Translational Research, 13, 2686-2693.
[14] 苏丹, 万星阳, 张恒, 等. 快速康复外科方案在肛肠良性疾病手术中的应用效果[J]. 实用医学杂志, 2021, 37(5): 626-631, 636.
[15] Hamed, M.A., Goda, A.S., Basiony, M.M., Fargaly, O.S. and Ahmed Abdelhady, M. (2019) Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy: A Randomized Controlled Study Original Study. Journal of Pain Research, 12, 1393-1398. [Google Scholar] [CrossRef] [PubMed]
[16] 陈小明, 胡饶, 万顺, 等. 混合痔外剥内扎切除术后发生尿潴留的危险因素及其预测模型的构建[J]. 武警医学, 2024, 35(7): 602-606.
[17] 孙天恒, 陈欢, 刘志顺. 五苓散类方治疗压力性尿失禁的临床应用[J]. 世界中医药, 2022, 17(10): 1459-1464.
[18] 曾丽, 郭乐, 胡小红. 穴位贴敷联合低频脉冲电疗防治产后尿潴留临床观察[J]. 中国中医药现代远程教育, 2024, 22(23): 110-112.
[19] 高莹, 徐治中, 季红霞, 等. 穴位贴敷和按摩预防肛瘘术后尿潴留的临床观察[J]. 中国社区医师, 2024, 40(23): 62-64.
[20] 屈玉华, 刘藤, 陈凤鸣, 等. 小茴香溻渍联合温灸盒灸防治混合痔术后尿潴留的临床观察[J]. 中国民间疗法, 2024, 32(5): 27-30.
[21] 周如赟. 五苓散加味对肾虚湿热型良性前列腺增生症TUPKP术后排尿症状的影响[D]: [硕士学位论文]. 成都: 成都中医药大学, 2024.
[22] 马佳颖, 袁慧, 尚乘, 等. 五苓散治疗水肿作用机制及研究进展[J]. 辽宁中医药大学学报, 2024, 26(9): 163-167.
[23] 李邱梦. 基于meta分析及网络药理学探讨五苓散治疗原发性肾病综合征疗效及机制[D]: [硕士学位论文]. 武汉: 湖北中医药大学, 2022.