补阳还五汤对血管性痴呆的效果分析
Analysis of the Effects of Buyang Huanwu Decoction on Vascular Dementia
摘要: 目的:探究补阳还五汤对于血管性痴呆(Vascular dementia, VaD)患者的治疗效果。方法:抽取2024年1~12月我们医院收治的80例VaD患者,通过双盲法分为实验组和对照组,对照组按常规治疗,实验组在常规治疗基础上联合补阳还五汤配合治疗。结果:治疗前,两组治疗相关指标对比无明显差异(P > 0.05);治疗后,实验组上述指标较对照组有所改善(P < 0.01)。结论:补阳还五汤可以显著改善VaD患者病情,本文也期待为VaD提供新的临床思路。
Abstract: Objective: To explore the therapeutic effect of Buyang Huanwu Decoction on patients with Vascular Dementia (VaD). Methods: A total of 80 patients with VaD treated in our hospital from January to December 2024 were randomly selected and divided into an experimental group and a control group using a double-blind method. The control group received conventional treatment, while the experimental group received Buyang Huanwu Decoction in conjunction with conventional treatment. Results: There were no significant differences in the treatment-related indicators between the two groups before treatment (P > 0.05). After treatment, the indicators in the experimental group showed improvement compared to the control group (P < 0.01). Conclusion: Buyang Huanwu Decoction can significantly improve the condition of patients with VaD. This study also aims to provide new clinical insights for the treatment of VaD.
文章引用:郭维芳, 李雄飞. 补阳还五汤对血管性痴呆的效果分析[J]. 临床医学进展, 2026, 16(3): 4056-4061. https://doi.org/10.12677/acm.2026.1631217

参考文献

[1] Bir, S.C., Khan, M.W., Javalkar, V., Toledo, E.G. and Kelley, R.E. (2021) Emerging Concepts in Vascular Dementia: A Review. Journal of Stroke and Cerebrovascular Diseases, 30, Article ID: 105864. [Google Scholar] [CrossRef] [PubMed]
[2] Akhter, F., Persaud, A., Zaokari, Y., Zhao, Z. and Zhu, D. (2021) Vascular Dementia and Underlying Sex Differences. Frontiers in Aging Neuroscience, 13, Article 720715. [Google Scholar] [CrossRef] [PubMed]
[3] Gustavsson, A., van Westen, D., Stomrud, E., Engström, G., Nägga, K. and Hansson, O. (2019) Midlife Atherosclerosis and Development of Alzheimer or Vascular Dementia. Annals of Neurology, 87, 52-62. [Google Scholar] [CrossRef] [PubMed]
[4] Battle, C.E., Abdul-Rahim, A.H., Shenkin, S.D., Hewitt, J. and Quinn, T.J. (2021) Cholinesterase Inhibitors for Vascular Dementia and Other Vascular Cognitive Impairments: A Network Meta-Analysis. Cochrane Database of Systematic Reviews, No. 2, CD013306. [Google Scholar] [CrossRef] [PubMed]
[5] 王峥, 林琳. 补阳还五汤联合西药治疗缺血性脑卒中后血管性痴呆疗效及对血清炎症因子、氧化应激指标和血管内皮活性物质的影响[J]. 现代中西医结合杂志, 2022, 31(4): 469-473, 490.
[6] Skoog, I. and Aevarsson, O. (2019) Epidemiology of Vascular Dementia in Europe. Cerebrovascular Disease and Dementia, CRC Press, 54-68.
[7] Wolters, F.J. and Ikram, M.A. (2019) Epidemiology of Vascular Dementia: Nosology in a Time of Epiomics. Arteriosclerosis, Thrombosis, and Vascular Biology, 39, 1542-1549. [Google Scholar] [CrossRef] [PubMed]
[8] Uwagbai, O. and Kalish, V.B. (2022) Reasure. StatPearls Publishing.
[9] Deardorff, W.J. and Grossberg, G.T. (2019) Behavioral and Psychological Symptoms in Alzheimer’s Dementia and Vascular Dementia. Handbook of Clinical Neurology, 165, 5-32. [Google Scholar] [CrossRef] [PubMed]
[10] 林楠, 郭文娟, 李佳霖, 等. 补阳还五汤改善血管性痴呆病人认知及生活能力疗效的Meta分析[J]. 中西医结合心脑血管病杂志, 2023, 21(4): 629-635.
[11] 袁佳欢, 赵彦超, 梁亚锋. 补阳还五汤联合针刺督脉四穴辅治血管性痴呆疗效观察[J]. 实用中医药杂志, 2022, 38(7): 1121-1123.
[12] 王洋岗, 周春燕, 任惠明, 等. 电针配合加味补阳还五汤对血管性痴呆患者记忆行为学、血清BDNF、VEGF及神经元凋亡相关分子表达的影响[J]. 中华中医药学刊, 2022, 40(5): 81-84, 268.
[13] 易艳兰, 熊瑜, 曹笑, 等. 补阳还五汤治疗血管性痴呆的研究概况[J]. 中国民族民间医药, 2020, 29(17): 76-79.
[14] 曲丹. 补阳还五汤联合茴拉西坦治疗血管性痴呆的疗效观察[J]. 临床医药文献电子杂志, 2019, 6(46): 137, 140.
[15] 白亮, 黄赛娥, 陈雨, 等. 补阳还五汤联合多奈哌齐治疗血管性痴呆40例[J]. 福建中医药, 2017, 48(5): 47, 49.