中西医结合治疗原发性高血压合并失眠的 研究进展
Research Progress on the Integrated Traditional Chinese and Western Medicine Treatment of Primary Hypertension Complicated by Insomnia
DOI: 10.12677/acm.2026.1641223, PDF,   
作者: 夏 玥:黑龙江中医药大学研究生院,黑龙江 哈尔滨;袁晖戍*:黑龙江中医药大学哈南分院心病科,黑龙江 哈尔滨
关键词: 中西医结合原发性高血压失眠进展Integrated Traditional Chinese and Western Medicine Primary Hypertension Insomnia Progression
摘要: 原发性高血压与失眠均为临床常见疾病,二者常合并存在、互为因果,形成恶性循环,显著增加心脑血管疾病风险。西医治疗虽能有效控制血压,但效果有限。中医药理论基于整体观念和辨证论治,在调节机体平衡、改善睡眠质量方面具有独特优势。本文系统综述了原发性高血压合并失眠的流行病学现状、中西医发病机制认识及中西医结合治疗进展,重点关注汤剂、针灸疗法、耳穴压豆等中医特色疗法联合常规西药的临床疗效,以期为临床实践提供参考。
Abstract: Primary hypertension and insomnia are both common clinical conditions that frequently coexist and interact causally, forming a vicious cycle that significantly increases the risk of cardiovascular and cerebrovascular diseases. While Western medical treatments can effectively control blood pressure, their efficacy remains limited. Traditional Chinese Medicine (TCM), grounded in holistic principles and syndrome differentiation, offers unique advantages in regulating bodily equilibrium and improving sleep quality. This systematic review examines the epidemiological status of primary hypertension with insomnia, the understanding of its pathogenesis from both Chinese and Western medical perspectives, and advances in integrated Chinese-Western treatment approaches. It focuses on the clinical efficacy of combining distinctive Chinese therapies—such as decoction therapy, acupuncture, and auricular acupressure—with conventional Western medications, aiming to provide practical guidance for clinical practice.
文章引用:夏玥, 袁晖戍. 中西医结合治疗原发性高血压合并失眠的 研究进展[J]. 临床医学进展, 2026, 16(4): 43-49. https://doi.org/10.12677/acm.2026.1641223

参考文献

[1] 国家心血管病中心, 中国心血管健康与疾病报告编写组, 胡盛寿. 中国心血管健康与疾病报告2023概要[J]. 中国循环杂志, 2024, 39(7): 625-660.
[2] 杨德业, 赵连友, 李玉明, 等. 中国继发性高血压临床筛查多学科专家共识(2023) [J]. 心脑血管病防治, 2023, 23(1): 1-24.
[3] Greenlund, I.M. and Carter, J.R. (2022) Sympathetic Neural Responses to Sleep Disorders and Insufficiencies. American Journal of Physiology-Heart and Circulatory Physiology, 322, H337-H349. [Google Scholar] [CrossRef] [PubMed]
[4] D’Aurea, C., Poyares, D., Piovezan, R.D., Passos, G.S., Tufik, S. and Mello, M.T.D. (2015) Objective Short Sleep Duration Is Associated with the Activity of the Hypothalamic-Pituitary-Adrenal Axis in Insomnia. Arquivos de Neuro-Psiquiatria, 73, 516-519. [Google Scholar] [CrossRef] [PubMed]
[5] 吴力菲, 陈竞纬. 高血压与失眠相关性中西医研究进展[J]. 辽宁中医药大学学报, 2020, 22(7): 196-199.
[6] 石鸿伟, 陈理. 高血压伴失眠的中西医临床研究进展[J]. 中外医学研究, 2024, 22(5): 162-166.
[7] Atrooz, F. and Salim, S. (2020) Sleep Deprivation, Oxidative Stress and Inflammation. Advances in Protein Chemistry and Structural Biology, 119, 309-336.
[8] Fang, H., Tu, S., Sheng, J. and Shao, A. (2019) Depression in Sleep Disturbance: A Review on a Bidirectional Relationship, Mechanisms and Treatment. Journal of Cellular and Molecular Medicine, 23, 2324-2332. [Google Scholar] [CrossRef] [PubMed]
[9] 杨丽娟, 孔乐亭, 王培培. 龙胆泻肝汤加减联合耳穴压豆辅助常规西药治疗不寐合并原发性高血压病临床研究[J]. 新中医, 2022, 54(23): 198-202.
[10] 富雪婷, 陈勇, 李雅璐. 酸枣仁汤联合常规西药治疗非杓型高血压合并失眠患者的效果及对睡眠质量的影响[J]. 大医生, 2024, 9(13): 87-90.
[11] 梁丽嫦, 黎煜斐, 郑浪花, 等. 赭决七味化裁方对气虚痰湿质高血压合并失眠患者的干预作用[J/OL]. 中国实验方剂学杂志, 2025: 1-10. 2026-03-25.[CrossRef
[12] 徐高阳, 戴悦晴. 松龄血脉康胶囊联合耳穴埋豆治疗肝阳上亢型高血压合并失眠的疗效观察[J]. 湖北中医杂志, 2025, 47(7): 43-45.
[13] 石鸿伟, 任飞, 周浩玲, 等. “和脉调神”针法治疗高血压伴失眠患者血压变异性及睡眠情况的临床研究[J]. 针灸临床杂志, 2025, 41(4): 18-23.
[14] 丁蕾, 刘雪燕, 戴淑青, 等. 针药结合治疗老年原发性高血压伴失眠的疗效观察[J]. 世界中西医结合杂志, 2022, 17(1): 137-141, 146.
[15] 吴家民, 吴锦镇, 罗超, 等. 耳穴贴压治疗高血压及其并发症的研究进展[J]. 针灸临床杂志, 2018, 34(11): 87-90.
[16] Javaheri, S. and Redline, S. (2017) Insomnia and Risk of Cardiovascular Disease. Chest, 152, 435-444. [Google Scholar] [CrossRef] [PubMed]
[17] Grassi, G., Dell’Oro, R., Quarti-Trevano, F., Vanoli, J. and Oparil, S. (2023) Sympathetic Neural Mechanisms in Hypertension: Recent Insights. Current Hypertension Reports, 25, 263-270. [Google Scholar] [CrossRef] [PubMed]
[18] 张琪, 李芳芳, 温欣, 等. 电针“太冲”改善两肾一夹型高血压大鼠的压力反射敏感性和孤束核α2肾上腺素受体活动[J]. 针刺研究, 2021, 46(3): 187-193.
[19] 刘俊昌, 张雪枫, 张星平, 等. 穴位埋线对失眠大鼠认知功能及5-HT、DA、GABA水平的影响[J]. 新疆医科大学学报, 2024, 47(9): 1301-1306.
[20] 汪学军, 何杏玲, 卢杏娟, 等. 天麻钩藤饮对自发性高血压大鼠血清Ca2+浓度及血管平滑肌细胞钙通道的影响[J]. 中国中医基础医学杂志, 2011, 17(11): 1217-1219.
[21] 辛二旦, 张爱霞, 司昕蕾, 等. 有助于改善睡眠的中药及其成分探究进展[C]//中国睡眠研究会. 中国睡眠研究会第十届全国学术年会汇编. 2018: 946-950.