瑞马唑仑与依托咪酯用于无痛胃肠镜检查的 镇静效果及安全性分析
Analysis of the Sedative Effects and Safety of Remimazolam and Etomidate in Painless Gastrointestinal Endoscopy
DOI: 10.12677/acm.2026.1641230, PDF,   
作者: 焦天明:新疆维吾尔自治区第二济困医院(新疆维吾尔自治区中西医结合医院,新疆维吾尔自治区第五人民医院)麻醉科,新疆 乌鲁木齐
关键词: 依托咪酯安全性无痛胃肠镜检查瑞马唑仑镇静效果Dexmedetomidine Safety Painless Gastrointestinal Endoscopy Remimazolam Sedation Effect
摘要: 目的:分析无痛胃肠镜检查中联合应用瑞马唑仑和依托咪酯的镇静效果与安全性。方法:随机选取从2025年10月~2026年2月,于本院行无痛胃肠镜检查的患者共52例,其中对照组为依托咪酯26例,观察组为依托咪酯结合瑞马唑仑麻醉26例并分析麻醉效果。结果:与对照组比,观察组血流动力学更平稳,改良警觉/镇静评分(MOAA/S)更低、依托咪酯总用量更少,苏醒及离院时间更短且不良反应发生占比低(P均<0.05)。结论:瑞马唑仑配合依托咪酯应用在无痛胃肠镜检查中,患者术中体征稳定,镇静效果佳,依托咪酯总药量少,恢复时间短且安全性高。
Abstract: Objective: To analyze the sedative effect and safety of the combined use of remifentanil and etomidate in painless gastroscopy. Method: A total of 52 patients who underwent painless gastrointestinal endoscopy in our hospital from October 2025 to February 2026 were randomly selected, with 26 cases in the control group receiving etomidate and 26 cases in the observation group receiving anesthesia with a combination of etomidate and remimazolam, followed by analysis of the anesthetic effects. Result: Compared with the control group, the observation group had smoother hemodynamics, lower Modified Alert/Sedation Score (MOAA/S), lower total dose of etomidate, shorter recovery and discharge time, and lower incidence of adverse reactions (all P < 0.05). Conclusion: The combination of remifentanil and etomidate in painless gastroscopy has stable intraoperative signs, good sedative effect, low total dose of etomidate, short recovery time, and high safety.
文章引用:焦天明. 瑞马唑仑与依托咪酯用于无痛胃肠镜检查的 镇静效果及安全性分析[J]. 临床医学进展, 2026, 16(4): 104-109. https://doi.org/10.12677/acm.2026.1641230

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