基于刘完素“火热论”探讨HPV感染性 宫颈炎癌转化

Exploring the Carcinogenic Transformation of HPV-Infected Cervicitis Based on Liu Wansu’s “Theory of Fire-Heat”

摘要: 刘完素提出“火热论”，内容主要包括“六气皆从火化”“五志过极皆为热甚”。炎症作为癌变的重要桥梁，其产生与火热毒邪密切相关。宫颈炎癌转化的诱发因素为邪气侵袭胞门，根本病机为湿热毒邪蕴结局部，内在条件在于正气亏虚，从而导致炎症发展为癌症。外感而导致的火热，反复日久；或五志失极郁结，从而气郁化火。治疗应根据不同阶段，炎症期为邪正交争，以清热利湿解毒为主；炎癌转化，以正气虚为主，治以健脾除湿止带；癌症已成，为改善预后，则需调和气血阴阳。

Abstract: Liu Wansu put forward the “Theory of Fire-Heat”, which mainly includes “all six climatic factors transform into fire” and “extreme manifestations of the five emotions all result from excessive heat”. Inflammation, as an important bridge to canceration, is closely related to fire-heat and toxic pathogens. The inducing factor for the transformation of cervicitis into cancer is the invasion of pathogenic factors into the uterine orifice. The fundamental pathogenesis is the accumulation of damp-heat and toxic pathogens in the local area, and the internal condition lies in the deficiency of healthy qi, which leads to the development of inflammation into cancer. Fire-heat caused by exogenous pathogens persists repeatedly over a long period; or extreme stagnation of the five emotions leads to qi stagnation transforming into fire. Treatment should be based on different stages: during the inflammatory stage, when healthy qi and pathogenic factors are contending, the main approach is to clear heat, drain dampness, and resolve toxins; during the inflammation-cancer transformation stage, when healthy qi deficiency is dominant, the treatment focuses on strengthening the spleen, eliminating dampness, and stopping leukorrhea; once cancer has developed, to improve the prognosis, it is necessary to regulate qi, blood, yin, and yang.