基于“骨肉不相亲”理论探讨老年骨质疏松性桡骨远端骨折的因机证治

Syndrome Differentiation and Treatment of Senile Osteoporotic Distal Radius Fractures: Insights from the “Bone and Muscle Are Not Closely Related” Theory

摘要: 现代医学研究表明，增龄性肌骨疾病的病理过程涉及骨与骨骼肌构成的协同功能单位。基于中医“骨肉不相亲”理论，本文系统探讨老年骨质疏松性桡骨远端骨折的病因病机及防治策略。研究揭示其本质在于脾肾双虚，病理表现为骨枯肉痿，核心是力学与功能关联的断裂。治疗关键在于“补肾壮骨，健脾生肌”的治本之法，阻断疾病传变进程。本研究为中医药防治老年骨质疏松性桡骨远端骨折及相关肌骨退行性疾病提供了创新性理论框架，虽需深化机制研究，但为中西医结合诊疗开辟了新的学术路径。

Abstract: Modern medical research indicates that the pathological processes of age-related musculoskeletal disorders involve the coordinated functional unit formed by bones and skeletal muscles. Based on the traditional Chinese medicine theory of “bone and muscle failing to maintain their intimate relationship”, this study systematically investigates the etiology, pathogenesis, and prevention strategies of osteoporotic distal radius fractures in elderly patients. The research reveals that the essential mechanism lies in the dual deficiency of the spleen and kidney: impaired renal function in governing bones and generating marrow, coupled with weakened splenic capacity in nutrient transportation and muscle regulation, leads to bone fragility and muscle atrophy, creating a fracture-prone state. The therapeutic cornerstone focuses on addressing the root cause through “tonifying the kidney to strengthen bones and invigorating the spleen to promote muscle regeneration”, thereby interrupting disease progression. This study provides an innovative theoretical framework for TCM-based prevention and treatment of osteoporotic distal radius fractures and related musculoskeletal degenerative diseases in the elderly. Although further mechanistic investigations are required, it establishes a novel academic pathway for integrated traditional Chinese and Western medicine approaches in clinical management.