骨质疏松椎体骨折微创治疗与综合管理进展
Advances in Minimally Invasive Treatment and Comprehensive Management of Osteoporotic Vertebral Fractures
DOI: 10.12677/acm.2026.1641309, PDF,    科研立项经费支持
作者: 周 波, 毕 尼, 张 立, 曹成泉, 赵 智, 王迎松*：昆明医科大学第二附属医院骨科，云南省教育厅脊柱畸形防治创新技术工程研究中心，云南 昆明
关键词: 骨质疏松性椎体压缩骨折；经皮椎体成形术；经皮椎体后凸成形术；骨水泥；精准医学；Osteoporotic Vertebral Compression Fracture； Percutaneous Vertebroplasty； Percutaneous Kyphoplasty； Bone Cement； Precision Medicine
摘要: 骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fracture, OVCF)作为骨质疏松症最常见的并发症，其发病率随人口老龄化进程不断攀升。目前，经皮椎体成形术(PVP)与经皮脊柱后凸成形术(PKP)已成为主流的外科干预方式，然而在术式选择、骨水泥材料优化、邻近椎体再发骨折的预防等关键临床问题上，仍存在诸多争议。本文旨在阐述OVCF的精准诊断策略、微创治疗技术的演进、围手术期管理要点以及抗骨质疏松治疗的最新进展，深入分析不同临床策略的循证医学依据与现存困境，并进一步展望智能化技术与新型生物材料在未来的应用前景。
Abstract: Osteoporotic vertebral compression fracture (OVCF), the most common complication of osteoporosis, has witnessed a continuously rising incidence alongside global population aging. Currently, percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) have emerged as the mainstream surgical interventions; however, substantial controversies persist regarding critical clinical issues, including surgical modality selection, optimization of bone cement biomaterials, and prophylaxis against adjacent vertebral refractures. This article aims to elucidate precise diagnostic strategies for OVCF, the evolution of minimally invasive therapeutic techniques, essential perioperative management considerations, and recent advances in anti-osteoporotic therapy. Furthermore, it provides an in-depth analysis of the evidence-based medical foundations and existing dilemmas underlying diverse clinical strategies, while prospectively examining the future applications of intelligent technologies and novel biomaterials.
文章引用：周波, 毕尼, 张立, 曹成泉, 赵智, 王迎松. 骨质疏松椎体骨折微创治疗与综合管理进展[J]. 临床医学进展, 2026, 16(4): 796-804. https://doi.org/10.12677/acm.2026.1641309

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