罗哌卡因用于儿童区域麻醉的应用进展
Advances in the Application of Ropivacaine for Pediatric Regional Anesthesia
DOI: 10.12677/acm.2026.1641316, PDF,   
作者: 杨 颖, 涂生芬*：重庆医科大学附属儿童医院麻醉科，儿童发育疾病研究教育部重点实验室，国家儿童健康与疾病临床医学研究中心，儿童发育重大疾病国家国际科技合作基地，重庆
关键词: 罗哌卡因；神经阻滞；儿童；Ropivacaine； Nerve Block； Pediatric
摘要: 罗哌卡因作为一种新型长效酰胺类局麻药，具有感觉–运动阻滞分离特性，且中枢神经和心血管系统毒性较低，已成为儿科区域麻醉的首选局麻药物。区域麻醉常用于围术期及非围术期的急慢性疼痛管理，可实现特定区域的精准镇痛，效果确切，联合超声可视化技术，安全性显著提升，更适用于儿童群体。根据临床研究发现，一定剂量的罗哌卡因用于合适的区域麻醉，能够满足儿童镇痛需求，减少了阿片类药物的使用量并降低相关不良反应发生率，有助于快速康复。因此，本文结合其药理机制，综述罗哌卡因用于儿童区域麻醉的临床研究。
Abstract: Ropivacaine, a novel long-acting amide local anesthetic, is characterized by sensory-motor separation and low central nervous system and cardiovascular toxicity, establishing it as the preferred agent for pediatric regional anesthesia. Regional anesthesia is widely employed for perioperative and non-perioperative acute and chronic pain management, enabling precise, site-specific analgesia with proven efficacy. The integration of ultrasound-guided technology has significantly enhanced its safety profile, particularly suitable for the pediatric population. Clinical evidence indicates that an appropriate dose of ropivacaine, when applied in suitable regional anesthesia techniques, effectively fulfills pediatric analgesic requirements, reduces opioid consumption, and lowers the incidence of associated adverse reactions, thereby facilitating enhanced recovery. Accordingly, this review synthesizes the pharmacological mechanisms of ropivacaine and summarizes its clinical applications in pediatric regional anesthesia.
文章引用：杨颖, 涂生芬. 罗哌卡因用于儿童区域麻醉的应用进展[J]. 临床医学进展, 2026, 16(4): 860-870. https://doi.org/10.12677/acm.2026.1641316

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