梓醇对心血管疾病保护作用的研究进展
Research Progress on the Cardiovascular Protective Effects of Catalpol
DOI: 10.12677/jcpm.2026.52110, PDF,   
作者: 王雯雯：济宁医学院临床医学院，山东 济宁；胡玲爱：济宁医学院附属医院心内科冠心病二病区，山东 济宁
关键词: 心血管疾病；梓醇；氧化应激；炎症；脂质代谢；Cardiovascular Disease； Catalpol； Oxidative Stress； Inflammation； Lipid Metabolism
摘要: 心血管疾病是全球发病率和死亡率最高的疾病之一，其严重威胁人类健康，寻找有效的心血管保护作用的药物至关重要。中药地黄具有清热凉血、滋阴清热等效果，梓醇是地黄的核心成分之一，近年来研究发现梓醇在心血管系统疾病(CVD)防治中具有多靶点、多途径的保护作用，在心血管疾病的防治和预防中展现其显著潜力。本篇文章从抗氧化、抗炎、抗凋亡等方面对梓醇保护心血管疾病进行综述，有望为日后梓醇在临床上的应用和相关药物的开发提供新思路和新方法。
Abstract: Cardiovascular diseases are among the most prevalent and fatal diseases worldwide, posing a serious threat to human health. Therefore, it is crucial to find effective drugs with cardiovascular protective effects. Rehmannia glutinosa, a traditional Chinese medicine, has effects such as clearing heat and cooling blood, nourishing yin and clearing heat. Verbenalin is one of the core components of Rehmannia glutinosa. Recent studies have found that verbenalin has multi-target and multi-pathway protective effects in the prevention and treatment of cardiovascular and cerebrovascular diseases (CVD), showing significant potential in the prevention and treatment of cardiovascular diseases. This article reviews the protective effects of verbenalin on cardiovascular diseases from aspects such as antioxidation, anti-inflammation, and anti-apoptosis, which is expected to provide new ideas and methods for the clinical application of verbenalin and the development of related drugs in the future.
文章引用：王雯雯, 胡玲爱. 梓醇对心血管疾病保护作用的研究进展[J]. 临床个性化医学, 2026, 5(2): 128-135. https://doi.org/10.12677/jcpm.2026.52110

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