肠道菌群在儿童过敏性鼻炎中的研究进展
Research Progress on Gut Microbiota in Pediatric Allergic Rhinitis
DOI: 10.12677/jcpm.2026.52119, PDF,   
作者: 王 敏, 周 晗*：西安医学院研究生工作部，陕西 西安
关键词: 肠道菌群；儿童过敏性鼻炎；免疫；Gut Microbiota； Pediatric Allergic Rhinitis； Immunity
摘要: 过敏性鼻炎(Allergic Rhinitis, AR)是过敏原作用于人体后，由特定细胞介导的超敏反应。AR作为儿童慢性过敏性疾病中高发频率的疾病之一，近年来AR发病率在全球呈上升趋势，对患儿的生活质量及家庭经济产生了极大负担。我们使用PubMed进行检索，使用以下关键词：肠道菌群与免疫，儿童肠道菌群影响因素，肠道菌群与儿童AR。所有年份的研究都包括在内。近年来微生态与AR之间的联系已成为广泛关注的热点问题，菌群失调在AR中多方面影响儿童健康。为了全面揭示微生态与儿童AR之间的联系，我们从菌群对人体免疫的作用讨论了其在AR中的重要影响，并对菌群影响因素进行了多方面阐述，以期为儿童AR与肠道菌群联系提供全面理解。
Abstract: Allergic rhinitis (AR) is a hypersensitivity reaction mediated by specific cells in response to allergens. As one of the most prevalent chronic allergic diseases in children, the global incidence of AR has been increasing in recent years, imposing a substantial burden on the quality of life of affected children and the economic status of their families. We conducted a search using PubMed with the following keywords: gut microbiota and immunity, factors influencing gut microbiota in children, and gut microbiota and pediatric AR. Studies from all years were included. In recent years, the association between the microbiota and AR has garnered widespread attention, with dysbiosis affecting the health of children with AR in multiple ways. To comprehensively elucidate the relationship between the microbiota and pediatric AR, we discussed the significant role of the microbiota in AR through its effects on the immune system and provided a multifaceted exploration of factors influencing the microbiota, aiming to offer a comprehensive understanding of the connection between the gut microbiota and AR in children.
文章引用：王敏, 周晗. 肠道菌群在儿童过敏性鼻炎中的研究进展[J]. 临床个性化医学, 2026, 5(2): 203-211. https://doi.org/10.12677/jcpm.2026.52119

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