多模态超声在胆管细胞癌中的应用研究
Research Progress of Multimodal Ultrasound in Cholangiocarcinoma
DOI: 10.12677/jcpm.2026.52121, PDF,   
作者: 兰景云：延安大学医学院，陕西 延安；王天娇, 郑 瑜*：西安交通大学附属西安市中心医院超声医学科，陕西 西安
关键词: 胆管细胞癌；超声检查；多模态超声；人工智能；超声造影；弹性成像；Cholangiocarcinoma； Ultrasonography； Multimodal Ultrasound； Artificial Intelligence； Contrast-Enhanced Ultrasound； Elastography
摘要: 胆管细胞癌(cholangiocarcinoma)是一种来源于胆管上皮的恶性肿瘤，居原发性肝癌的第二位，预后极差。其早期常无明显临床症状，确诊多在中晚期，严重影响患者生存。超声检查作为无创、实时、方便的首选成像手段，对于胆道疾病的早期筛查有重要价值。近年来，多维度和多模态超声技术(包括二维、三维/四维、多普勒、弹性成像及超声造影等)在胆管癌诊断和分型方面取得了重大进展。同时，人工智能和辐射组学的快速发展为超声图像分析带来了新思路。本文综述了多模态超声在胆管细胞癌中的应用进展，重点介绍了人工智能辅助诊断和多模态超声融合在胆管癌早期识别、病理分型、治疗指导及预后评估中的研究成果与临床前景。
Abstract: Cholangiocarcinoma is a malignant tumor arising from the biliary epithelium and the second most common primary liver cancer, with extremely poor prognosis. Because of its insidious onset, most cases are diagnosed at advanced stages, missing optimal treatment opportunities. Ultrasound, as a noninvasive and convenient first-line imaging modality, plays a key role in initial detection of biliary tract lesions. In recent years, multidimensional ultrasound techniques (including 2D, 3D/4D, Doppler, elastography, and contrast-enhanced ultrasound) and artificial intelligence (AI) have significantly advanced the early detection and characterization of cholangiocarcinoma. This review summarizes the progress of multimodal ultrasound and AI-assisted diagnosis in cholangiocarcinoma, highlighting their applications in early identification, subtype classification, treatment planning, and prognostic evaluation.
文章引用：兰景云, 王天娇, 郑瑜. 多模态超声在胆管细胞癌中的应用研究[J]. 临床个性化医学, 2026, 5(2): 216-225. https://doi.org/10.12677/jcpm.2026.52121

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