稳心颗粒治疗早搏的临床疗效观察

Clinical Observation on the Therapeutic Effect of Wenxin Granules in Treating Premature Beats

摘要: 目的：观察稳心颗粒治疗早搏的临床疗效。方法：将2023年至2025年天津中医药大学第二附属医院心内科门诊和住院的早搏患者200例，随机分为对照组和治疗组，每组100例。对照组给予常规治疗，治疗组在常规治疗基础上，口服稳心颗粒，1次1袋，1日3次；两组疗程均为2周。观察两组患者房性早搏、室性早搏次数变化及中医临床证候积分变化，并评价临床疗效。结果：两组患者治疗后，房性早搏和室性早搏均显著降低；与治疗前组内比较，差异均具有统计学意义(P < 0.05)；与对照组比较，治疗组治疗后的房性早搏和室性早搏降低程度更明显，差异均具有统计学意义(P < 0.05)。治疗后，两组患者的心悸气短、胸闷憋气、失眠多梦症状积分均较治疗前改善，差异具有统计学意义(P < 0.05)，但是对照组的神疲乏力症状积分改善不明显；两组患者治疗后，治疗组总有效率高于对照组，差异有统计学意义(P < 0.05)。结论：稳心颗粒能够显著减少房性早搏和室性早搏次数，同时有效改善心悸气短、胸闷憋气、神疲乏力、失眠多梦等证候积分，并且显著提高临床疗效，在临床上具有良好的推广前景与应用意义。

Abstract: Objective: To observe the clinical efficacy of Wenxin Granules in the treatment of premature beats. Methods: A total of 200 premature beat patients admitted to the outpatient and inpatient departments of Cardiology, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from 2023 to 2025 were randomly divided into a control group and a treatment group, with 100 cases in each group. The control group received conventional treatment. On the basis of conventional treatment, the treatment group received Wenxin granules orally, 1 bag per dose, 3 times a day. Patients in both groups were observed for 2 weeks. Observe the changes in the frequency of atrial premature beats, ventricular premature beats, and the changes in TCM clinical syndrome scores to evaluate clinical efficacy. Results: After treatment, atrial premature beats and ventricular premature beats were significantly reduced in the two groups of patients. Compared with those in the group before treatment, the differences were statistically significant (P < 0.05); compared with the control group, the reduction of atrial premature beats and ventricular premature beats was more obvious, and the difference was statistically significant (P < 0.05). After treatment, the symptom scores of palpitations and shortness of breath, chest tightness and breathlessness, and insomnia with dream-disturbed sleep in both groups were improved compared with those before treatment, with statistically significant differences (P < 0.05), but the improvement of the symptoms of fatigue and fatigue in the control group was not significant; After the two groups of patients were treated, the total effective rate of the treatment group was higher than that of the control group, and the difference was statistically significant (P < 0.05). Conclusion: Wenxin granule can significantly reduce the frequency of atrial premature beats and ventricular premature beats, and at the same time effectively improve palpitations and shortness of breath, chest tightness and breathlessness, fatigue and weakness, and insomnia with dream-disturbed sleep, and significantly improve the clinical efficacy. Clinically, it is worth promoting the efficacy and value of Wenxin Granules in treating arrhythmia.