心肌酶谱与急性下肢缺血患者截肢率的相关性分析
Correlation Analysis between Myocardial Enzyme Profile and Amputation Rate in Patients with Acute Lower Extremity Ischemia
摘要: 急性下肢缺血(Acute Lower Limb Ischemia, ALLI)是血管外科常见的急重症，核心挑战在于如何在有限的时间窗内准确研判肢体活力。早期准确评估缺血肢体的肌肉活力对于制定保肢或截肢策略至关重要。传统影像学检查在量化骨骼肌坏死程度方面存在局限性。本文旨在系统评价心肌酶谱(包括肌酸激酶CK、乳酸脱氢酶LDH、天门冬氨酸氨基转移酶AST等)水平与ALLI患者肢体坏死程度及截肢率的相关性，探讨其在外科临床决策中的潜在价值。
Abstract: Acute lower limb ischemia (ALLI) is a common and critical emergency in vascular surgery. The core challenge lies in accurately determining limb viability within a limited time window. Early and accurate assessment of muscle viability in the ischemic limb is crucial for formulating limb salvage or amputation strategies. Traditional imaging modalities have limitations in quantifying the extent of skeletal muscle necrosis. This article aims to systematically evaluate the correlation between myocardial enzyme profiles (including creatine kinase [CK], lactate dehydrogenase [LDH], aspartate aminotransferase [AST], etc.) and the severity of limb necrosis and amputation rates in ALLI patients, exploring their potential value in surgical clinical decision-making.
文章引用：吴国栋, 刘仁贵, 龙远航. 心肌酶谱与急性下肢缺血患者截肢率的相关性分析[J]. 临床个性化医学, 2026, 5(2): 413-420. https://doi.org/10.12677/jcpm.2026.52141

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