抗抑郁药物中毒机制的研究进展
Research Progress on the Mechanisms of Antidepressant Drug Poisoning
DOI: 10.12677/acm.2026.1641436, PDF,   
作者: 何 莹, 刘丽萍, 文 静, 赵群远, 陈安宝*:昆明医科大学第二附属医院急诊科,云南 昆明
关键词: 抑郁症抗抑郁药物中毒机制临床特征Depression Antidepressants Poisoning Mechanism Clinical Features
摘要: 抗抑郁药物种类繁多,中毒机制复杂多样,过量摄入或中毒可引起多个系统毒性反应,例如心脏毒性、中枢神经系统抑制、癫痫发作、抗胆碱能毒性、5-羟色胺综合征等,严重时可危及生命。了解不同抗抑郁药物的中毒机制及其所引起的临床特征,对提高救治成功率、改善患者预后具有重要意义。本文通过总结近几年抗抑郁药物中毒机制的最新研究进展,以期为临床合理诊治提供参考依据。
Abstract: There are numerous types of antidepressants with complex and diverse poisoning mechanisms. Overdose or poisoning can cause toxic reactions in multiple systems, such as cardiotoxicity, central nervous system depression, seizures, anticholinergic toxicity, and serotonin syndrome, which can be life-threatening in severe cases. Understanding the poisoning mechanisms of different antidepressants and their clinical features is of great significance for improving treatment success rates and patient outcomes. This article summarizes the latest research progress on antidepressant poisoning mechanisms in recent years, aiming to provide a reference for rational clinical diagnosis and treatment.
文章引用:何莹, 刘丽萍, 文静, 赵群远, 陈安宝. 抗抑郁药物中毒机制的研究进展[J]. 临床医学进展, 2026, 16(4): 1942-1951. https://doi.org/10.12677/acm.2026.1641436

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