王克勤教授从“肝气虚、阴精亏虚”论治慢性精神分裂症经验

Professor Wang Keqin’s Experience in Treating Chronic Schizophrenia from the Perspective of “Liver Qi Deficiency and Yin Essence Deficiency”

摘要: 慢性精神分裂症病程迁延，阴性症状突出，而西药治疗存在副作用与高复发率等多个问题，中医药在整体调节、改善阴性症状及生活质量方面具有独特优势。王克勤教授基于多年临证经验，创新性的提出“肝气虚”与“阴精亏虚”为该病迁延难愈的重要病机，补前人所未备。本文系统总结王克勤教授对慢性精神分裂症的病因病机认识、治疗原则与用药经验，并通过两则典型医案举例加以补充，探讨其“益气填精固本，化痰开窍治标，分期论治调方”的治疗思路，为中医药治疗慢性精神分裂症提供了新视角。

Abstract: Chronic Schizophrenia is characterized by a prolonged course and prominent negative symptoms. While Western medicine faces challenges such as side effects and high relapse rates, traditional Chinese medicine offers unique advantages in holistic regulation, improving negative symptoms, and enhancing quality of life. Based on years of clinical experience, Professor Wang Keqin has innovatively proposed “liver qi deficiency” and “yin essence deficiency” as key pathological mechanisms underlying the persistent and refractory nature of this condition, supplementing previously unrecognized aspects. This article systematically summarizes Professor Wang’s understanding of the etiology and pathogenesis, treatment principles, and medication strategies for Chronic Schizophrenia. Two representative medical cases are included to illustrate his therapeutic approach, which emphasizes “tonifying qi and replenishing essence to consolidate the root, resolving phlegm and opening orifices to address the branch, and staging treatment with tailored prescriptions.” This provides a new perspective for the treatment of chronic schizophrenia with traditional Chinese medicine.