眼眶脉管瘤伴慢性炎症病例报道一例 并文献复习
Orbital Vascular Tumors and Malformations Complicated with Chronic Inflammation: A Case Report and Literature Review
DOI: 10.12677/acm.2026.1641490, PDF,   
作者: 罗 煜*, 陈宗至*, 陈昌胜：贵州医科大学医学影像学院，贵州 贵阳；赵许亚#：贵州省第二人民医院肿瘤与血管介入科，贵州 贵阳
关键词: 眼眶；脉管瘤；慢性炎症；诊断；Orbit； Vascular Tumors； Chronic Inflammation； Diagnosis
摘要: 眼眶脉管瘤伴慢性炎症较为罕见，其临床表现和影像学特征均不典型，术前被误诊为泪腺混合瘤，易致漏诊、误诊及晚诊。本病例报告旨在通过分享一例经手术及病理证实的眼眶脉管瘤伴慢性炎症，对于不典型的眼眶肿块，临床医生需在日常诊断中考虑本病可能性，探讨其诊断思路，以提升临床认识，减少漏诊与误诊，坚持以病理检查作为确诊的关键依据，以促进该类疾病的早期发现与规范治疗。
Abstract: Orbital vascular tumor with chronic inflammation is relatively rare, and its clinical manifestations and imaging features are both atypical. Preoperatively, it is easily misdiagnosed as a mixed tumor of the lacrimal gland, which can lead to missed diagnosis, misdiagnosis, and delayed diagnosis. This case report aims to share a surgically and pathologically confirmed case of orbital vascular tumor with chronic inflammation. For atypical orbital masses, clinicians should consider this possibility in the ordinary diagnosis. We discuss the diagnostic approach to enhance clinical recognition, reduce missed and misdiagnoses, and emphasize histopathological examination as the key basis for definitive diagnosis, thereby promoting early detection and standardized management of this disease.
文章引用：罗煜, 陈宗至, 陈昌胜, 赵许亚. 眼眶脉管瘤伴慢性炎症病例报道一例 并文献复习[J]. 临床医学进展, 2026, 16(4): 2408-2414. https://doi.org/10.12677/acm.2026.1641490

参考文献

[1] Chiou, C.A., Vickery, T.W., Reshef, E.R., Bleier, B.S. and Freitag, S.K. (2023) Endonasal Endoscopic Approach to Orbital Tumors. International Ophthalmology Clinics, 63, 249-262. [Google Scholar] [CrossRef] [PubMed]
[2] 张特, 杨华胜. 非典型影像表现的眼眶孤立性纤维瘤1例[J]. 中国眼耳鼻喉科杂志, 2024, 24(S1): 38-41.
[3] Sato, Y., Sakai, A., Ebisumoto, K., et al. (2025) A Rare Case of Hemangioma in the Thyroid: Clinical Presentation and Management Insights. The Tokai Journal of Experimental and Clinical Medicine, 50, 81-84.
[4] Kulchavenya, E., Naber, K. and Bjerklund Johansen, T.E. (2016) Urogenital Tuberculosis: Classification, Diagnosis, and Treatment. European Urology Supplements, 15, 112-121. [Google Scholar] [CrossRef] 
[5] 杜军伟. 颅内脉管瘤1例[J]. 中国医学影像技术, 2024, 40(4): 574.
[6] 魏昌晟, 包蔚郁, 姜专基, 等. 乳腺脉管瘤1例报告并文献复习[J]. 甘肃医药, 2024, 43(8): 762-764.
[7] 陈向志, 刘安甫, 刘润生. 脾脉管瘤1例[J]. 实用放射学杂志, 2008, 24(7): 1008.
[8] 石昌龙, 宋永胜. 膀胱脉管瘤1例报告[J]. 现代泌尿外科杂志, 2018, 23(10): 802-803.
[9] 李泽浩, 隋建美, 韩锋, 等. 椎管内硬膜外脉管瘤1例报告并文献复习[J]. 临床神经外科杂志, 2022, 19(5): 561-564.
[10] 刘丽燕, 蔡世捷. 回盲部脉管瘤2例临床病理分析并文献复习[J]. 福建医药杂志, 2023, 45(1): 91-93.
[11] Sindwani, R., Sreenath, S.B. and Recinos, P.F. (2024) Endoscopic Endonasal Approach to Intraconal Orbital Tumors: Outcomes and Lessons Learned. The Laryngoscope, 134, 47-55. [Google Scholar] [CrossRef] [PubMed]
[12] 王金鹏, 钞蕴昕, 杨贞, 等. 眶内脉管瘤1例[J]. 山东大学耳鼻喉眼学报, 2009, 23(6): 29-30.
[13] 裴雪艳, 于锦涛, 王琰. 下咽脉管瘤1例报道并文献复习[J]. 中国医刊, 2019, 54(9): 1002-1005.
[14] Sullivan, H.C., Edgar, M.A., Cohen, C., Kovach, C.K., et al. (2014) The Utility of ERG, CD31 and CD34 in the Cytological Diagnosis of Angiosarcoma: An Analysis of 25 Cases. Journal of Clinical Pathology, 68, 44-50. [Google Scholar] [CrossRef] [PubMed]
[15] Vosough, Z., Golbini, S., Sharbatdaran, M., et al. (2021) D2-40 a Helpful Marker in Assessment of Lymphatic Vessel Invasion in Carcinoma of Breast. Iranian Journal of Pathology, 16, 96-102.
[16] Machado-Santos, J., Saji, E., Tröscher, A.R., Paunovic, M., Liblau, R., Gabriely, G., et al. (2018) The Compartmentalized Inflammatory Response in the Multiple Sclerosis Brain Is Composed of Tissue-Resident CD8+ T Lymphocytes and B Cells. Brain, 141, 2066-2082. [Google Scholar] [CrossRef] [PubMed]
[17] Rimondi, E., Benassi, M.S., Bazzocchi, A., Balladelli, A., Facchini, G., Rossi, G., et al. (2016) Translational Research in Diagnosis and Management of Soft Tissue Tumours. Cancer Imaging, 16, Article No. 13. [Google Scholar] [CrossRef] [PubMed]
[18] Su, C., Jiang, J., Zhang, S., Shi, J., Xu, K., Shen, N., et al. (2019) Radiomics Based on Multicontrast MRI Can Precisely Differentiate among Glioma Subtypes and Predict Tumour-Proliferative Behaviour. European Radiology, 29, 1986-1996. [Google Scholar] [CrossRef] [PubMed]
[19] Kong, M., Li, Y., Wang, K., Zhang, S. and Ji, Y. (2023) Infantile Hemangioma Models: Is the Needle in a Haystack? Journal of Translational Medicine, 21, Article No. 308. [Google Scholar] [CrossRef] [PubMed]
[20] De Gaetano, V., Pallozzi, M., Cerrito, L., Santopaolo, F., Stella, L., Gasbarrini, A., et al. (2024) Management of Portal Hypertension in Patients with Hepatocellular Carcinoma on Systemic Treatment: Current Evidence and Future Perspectives. Cancers, 16, Article No. 1388. [Google Scholar] [CrossRef] [PubMed]
[21] Kahana, A., Lee, B.J., Flint, A. and Elner, V.M. (2012) Periocular Epithelioid Hemangioma: Response to Bevacizumab and Vascular Pathogenesis. Archives of Ophthalmology, 130, 1209-1212. [Google Scholar] [CrossRef] [PubMed]
[22] Nagasaka, M., Naganuma, H. and Satoh, E. (2007) Growth Potential of Orbital Cavernous Hemangioma Suggested by Vascular Endothelial Growth Factor and Its Receptor Flk-1. Neurologia Medico-Chirurgica, 47, 5-10. [Google Scholar] [CrossRef] [PubMed]
[23] Hamamin, O.S., Abdulrahman, S.W., Abdul Aziz, J.M., Rashid, M.J. and Hashan, M.R. (2026) Cavernous Hemangioma: A Rare Case Report in the Maxillary Sinus. Annals of Medicine & Surgery, 88, 809-813. [Google Scholar] [CrossRef] 
[24] Sharma, A.K., Sharma, R., Misra, S., Misra, N., Ashik, R., Hussain, N., et al. (2022) Pleomorphic Adenoma of the Orbital Ectopic Lacrimal Gland: An Extremely Rare Occurrence with Review of Literature. Neurology India, 70, 296-299. [Google Scholar] [CrossRef] [PubMed]
[25] 刘凤权. 泪腺上皮性肿瘤CT和MRI特征分析及泪腺多形性腺瘤临床研究[D]: [硕士学位论文]. 重庆: 第二军医大学, 2017.
[26] Yang, M. and He, W. (2024) Age and Gender Influence on Clinical Manifestations of Thyroid-Associated Ophthalmopathy: A Case Series of 2479 Chinese Patients. Frontiers in Endocrinology, 15, Article 1434155. [Google Scholar] [CrossRef] [PubMed]

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