TyG指数、TyG-BMI指数及RDW与冠脉病变支数及严重程度的研究进展
Research Progress on the Relationship between TyG Index, TyG-BMI Index, RDW and the Number and Severity of Coronary Artery Lesions
摘要: 冠状动脉粥样硬化性心脏病(Coronary Heart Disease, CHD)目前仍然属于全球心血管疾病中主要的类型，对于人类的生命健康已经产生了严重的危害。其中胰岛素抵抗可以通过炎症、氧化应激等多种途径参与并且作用于冠状动脉疾病的发生发展过程中。现在已经有研究表明，甘油三酯葡萄糖指数(TyG指数)、甘油三酯葡萄糖体质量指数(TyG-BMI指数)两个都是胰岛素抵抗(Insulin Resistance, IR)的一种新型替代评估指标，与冠状动脉疾病的发生发展及冠状动脉的严重程度有着重要的意义；而红细胞分布宽度(RDW)，作为血液学的指标，最近几年随着对于临床研究不断深入的过程中，RDW被发现与炎症反应以及心血管疾病有着密切的联系。因此本文就TyG指数、TyG-BMI指数及RDW与冠脉病变支数及严重程度相关性的研究进展进行综述。
Abstract: Coronary heart disease (CHD) remains one of the major types of cardiovascular disease globally and poses a serious threat to human health. Insulin resistance plays a role in the onset and progression of coronary artery disease through various mechanisms, including inflammation and oxidative stress. Recent studies have shown that the triglyceride-glucose index (TyG index) and the triglyceride-glucose body mass index (TyG-BMI index) are novel surrogate markers for insulin resistance (IR), both of which are significantly associated with the occurrence, development, and severity of coronary artery disease. Meanwhile, red blood cell distribution width (RDW), a hematological parameter, has recently been found to be closely related to inflammation and cardiovascular disease as clinical research deepens. Therefore, this paper reviews the current research progress on the correlations among the TyG index, TyG-BMI index, RDW, and the number and severity of coronary artery lesions.
文章引用：魏麟博, 孙宓颖. TyG指数、TyG-BMI指数及RDW与冠脉病变支数及严重程度的研究进展[J]. 临床医学进展, 2026, 16(4): 2457-2466. https://doi.org/10.12677/acm.2026.1641496

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