基于CiteSpace的半夏泻心汤治疗消化系统疾病的可视化分析

Visualization Analysis of Banxia Xiexin Decoction in the Treatment of Digestive System Diseases Based on CiteSpace

摘要: 目的：基于文献计量学方法，系统梳理半夏泻心汤治疗消化系统疾病的研究现状、核心协作网络及热点演化趋势。方法：检索中国知网自建库起至2026年2月24日收录的半夏泻心汤治疗消化系统疾病的相关文献。利用CiteSpace 6.4.R1软件，对发文量、作者、机构、关键词进行可视化分析。结果：最终纳入文献1597篇。发文量总体呈上升趋势，2015年起进入爆发式增长期。形成了以刘喜平、李宇航等为首的研究团队及天津、北京中医药大学等核心机构，但跨区域协作较少。研究重心已由传统“痞满”证治规律转向“病证结合”研究，涵盖慢性胃炎、幽门螺杆菌感染及功能性消化不良等病种。目前，“网络药理学”、“胃癌”及“四联疗法”等构成研究前沿。结论：半夏泻心汤在消化系统疾病中的应用范围持续扩大，研究范式正经历从临床经验总结向分子网络机制及肿瘤防治深化的转型。

Abstract: Objective: This study aims to systematically review the research status, core collaborative networks, and evolving trends of Banxia Xiexin Decoction (BXD) in the treatment of digestive system diseases, utilizing bibliometric methods. Methods: Literature related to BXD in treating digestive system diseases was retrieved from the China National Knowledge Infrastructure (CNKI) database from its inception to February 24, 2026. CiteSpace 6.4.R1 software was employed to perform visualization analysis on the volume of publications, authors, institutions, and keywords. Results: A total of 1,597 articles were ultimately included. The overall volume of publications exhibits an upward trend, entering a period of explosive growth since 2015. Research teams led by prominent scholars such as Liu Xiping and Li Yuhang, alongside core institutions like Tianjin University of Traditional Chinese Medicine and Beijing University of Chinese Medicine, have been established; however, cross-regional collaboration remains limited. The research focus has shifted from the traditional rules of “Piman” (epigastric fullness) syndrome and treatment to “integration of disease and syndrome” studies, encompassing conditions such as chronic gastritis, Helicobacter pylori infection, and functional dyspepsia. Currently, “network pharmacology,” “gastric cancer,” and “quadruple therapy” constitute the research frontiers in this field. Conclusion: The application of BXD in digestive system diseases continues to expand. The research paradigm is undergoing a significant transformation from clinical experience summaries toward deep exploration of molecular network mechanisms and tumor prevention and treatment.