金陵医派–金陵女科陈霞教授治疗肾虚血瘀型子宫腺肌病用药经验分析

Analysis of Medication Experience of Professor Chen Xia from Jinling Women’s Medicine of Jinling Medical School in Treating Kidney Deficiency and Blood Stasis Type of Adenomyosis

摘要: 研究收集了101例陈霞教授在南京市中医院治疗肾虚血瘀型子宫腺肌病的病例。采用数据挖掘技术，通过运用中医药传承计算平台(V3.5)分析药物的气味、归经、药性，并结合金陵医派的特点，得出陈霞教授的用药规律。结果显示，在101例病例中，使用频次前5的中药依次为赤芍(95次)、续断(82次)、醋香附(78次)、炙甘草(76次)、醋延胡索(76次)。所用药物四气多为温、平、寒，五味多为甘、苦、辛，主归肝、脾、心经；药物种类以补虚药为主，其次为活血化瘀药、清热药、利水渗湿药和理气药；用药组合出现频次前5的依次为赤芍–续断(78次)、赤芍–醋香附(73次)、赤芍–炙甘草(69次)、赤芍–醋延胡索(69次)、续断–醋香附(65次)。可以发现，陈霞教授治疗肾虚血瘀型子宫腺肌病具有用药平和、顾护脾胃、形神共治的特点。

Abstract: This study collected 101 cases of adenomyosis with kidney deficiency and blood stasis pattern treated by Professor Chen Xia at Nanjing Hospital of Chinese Medicine. Data mining technology was used to derive Professor Chen Xia’s pattern of medication use by TCMICS (V3.5) to analyze the odor, attributed meridians, and medicinal properties of the medicines, and combining them with the characteristics of Jinling Medical School, to identify Professor Chen Xia’s medication patterns. The results showed that among the 101 cases, the top 5 Chinese medicines used frequently were, in order, Chishao (Radix Paeoniae Rubra, 95 times), Xuduan (Radix Dipsaci, 82 times), Cu Xiangfu (Vinegar-processed Rhizoma Cyperi, 78 times), Zhigancao (Honey-fried Radix et Rhizoma Glycyrrhizae, 76 times), and Cu Yanhusuo (Vinegar-processed Rhizoma Corydalis, 76 times). The four properties of the herbs were predominantly warm, neutral, and cold; the five flavors were mainly sweet, bitter, and pungent; and the primary channel affiliations were liver, spleen, and heart. The types of drugs used were mainly drugs to tonify deficiency, followed by drugs to activate blood circulation and remove blood stasis, clearing heat, diuresis, and dampness, and regulating Qi. The top five combinations of the drugs used were, in order of frequency, Chishao-Xuduan (78 times), Chishao-Cu Xiangfu (73 times), Chishao-Zhigancao (69 times), Chishao-Cu Yanhusuo (69 times), and Xuduan-Cu Xiangfu (65 times). These findings reveal that Professor Chen Xia’s treatment of adenomyosis with kidney deficiency and blood stasis pattern is characterized by moderate medication, protection of the spleen and stomach, and simultaneous treatment of physical and mental aspects.