右美托咪定在儿童围术期应用的研究进展
Research Progress on the Application of Dexmedetomidine in the Perioperative Period of Children
DOI: 10.12677/acm.2026.1641563, PDF,   
作者: 方璐瑶, 唐 文*：重庆医科大学附属儿童医院麻醉科，重庆
关键词: 右美托咪定；镇痛；镇静；儿童；Dexmedetomidine； Analgesia； Sedation； Children
摘要: 右美托咪定(Dexmedetomidine, DEX)作为一种新型α2肾上腺素能受体激动剂，其高受体特异性、多重药理特性及无显著呼吸抑制的独特优势，已在儿童围术期广泛应用。本文主要综述其在儿童术前抗焦虑、术中麻醉优化、术后镇痛管理及重症监护(PICU)中的应用进展。探讨右美托咪定在儿童麻醉领域的安全性与应用潜力，旨在为临床实践提供循证依据。
Abstract: Dexmedetomidine (DEX), as a new type of α2-adrenergic receptor agonist, has been widely used in the perioperative period of children due to its high receptor specificity, multiple pharmacological properties, and the unique advantage of no significant respiratory depression. This article mainly reviews its application progress in preoperative anti-anxiety, intraoperative anesthesia optimization, postoperative analgesia management, and Pediatric Intensive Care Unit (PICU) in children. It discusses the safety and application potential of dexmedetomidine in the field of pediatric anesthesia, aiming to provide an evidence-based basis for clinical practice.
文章引用：方璐瑶, 唐文. 右美托咪定在儿童围术期应用的研究进展[J]. 临床医学进展, 2026, 16(4): 3047-3052. https://doi.org/10.12677/acm.2026.1641563

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